| Type | Description |
|---|---|
| Definition | DNA-binding transcriptional dual regulator IscR |
| Date | Results | Publications |
|---|---|---|
| 2017-07-22 12:27:00 | findings show how an sRNA, RyhB, and a transcription factor, IscR, regulate expression of an essential gene, erpA, in E. coli | 27651365 |
| 2015-01-10 10:19:00 | Authors demonstrate that in the absence of isc, IscR-dependent suf activation is essential since strains lacking both the Isc pathway and IscR were not viable unless Suf was expressed ectopically. | 25266384 |
| 2013-08-31 12:04:00 | These data suggest a unique mechanism of ligand-mediated DNA site recognition, whereby metallocluster ligation relocates a protein-specificity determinant to expand DNA target-site selection, allowing a broader transcriptomic response by holo-IscR. | 23644595 |
| 2013-07-06 12:30:00 | Fe-S clusters directed at the apo-NsrR and apo-IscR proteins are built on either of the two scaffolds, IscU or SufB. | 23320508 |
| 2013-07-06 10:43:00 | Together, these data show how transcriptional control of iscRSUA-hscBA-fdx by [2Fe-2S]-IscR allows E. coli to respond efficiently to varying Fe-S demands. | 23075318 |
| Type | IDs |
|---|---|
| Synonymous | ECK2528, yfhP |
| Gene |
UniProtKB-ID:
ISCR_ECOLI
UniprotKB:
P0AGK8
UniParc:
UPI000013AE9A
EMBL:
AP009048,
U00096
EnsemblGenome:
b2531,
BAA16425
KO:
ecj:JW2515,
eco:b2531
|
| Nucleutide sequences |
EMBL-CDS:
BAA16425.1,
AAC75584.1
EnsemblGenome_TRS:
BAA16425,
AAC75584
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC75584,
BAA16425
RefSeq:
NP_417026.1
|
| Others |
UniRef100:
UniRef100_A7ZPX5
UniRef90:
UniRef90_A8AD51
UniRef50:
UniRef50_Q9KTY3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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