| Type | Description |
|---|---|
| Definition | SeqA, negative modulator of initiation of replication |
| Date | Results | Publications |
|---|---|---|
| 2015-06-27 10:22:00 | Data indicate that the SeqA protein is localized at midcell for most of the D-period, but colocalizes with the origin region before cell division and initiation of replication. | 25722374 |
| 2015-02-28 12:51:00 | Data suggest that, in the absence of SeqA, the sister-chromatid cohesion 'safety spacer' is destabilized and completely disappears if the replication fork is inhibited. | 24806348 |
| 2014-03-22 11:22:00 | We propose that SeqA binding results in loose inter-duplex junctions that are resistant to Topo IV cleavage | 23990792 |
| 2012-10-06 10:21:00 | Cell cycle analysis showed that loss of SeqA from the old replication forks did not occur at initiation of the new forks, but instead occurs at a time point coinciding with the end of SeqA-dependent origin sequestration. | 22373925 |
| 2010-03-22 11:57:00 | The number of SeqA foci is not directly governed by the number of replication forks, and supports the idea that new DNA may be 'captured' by existing SeqA structures. | 19371375 |
| Type | IDs |
|---|---|
| Synonymous | ECK0675, hsm-1 |
| Gene |
UniProtKB-ID:
SEQA_ECOLI
UniprotKB:
P0AFY8
UniParc:
UPI0000135864
EMBL:
U00096,
AP009048,
U07651
EnsemblGenome:
b0687,
BAA35336
KO:
ecj:JW0674,
eco:b0687
|
| Nucleutide sequences |
EMBL-CDS:
AAC73781.1,
AAA19855.1,
BAA35336.1
EnsemblGenome_TRS:
AAC73781,
BAA35336
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73781,
BAA35336
RefSeq:
NP_415213.1
|
| Others |
UniRef100:
UniRef100_P0AFY9
UniRef90:
UniRef90_P0AFY9
UniRef50:
UniRef50_F2EP55
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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