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945240 mrdA

945240

mrdA

peptidoglycan DD-transpeptidase MrdA

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition peptidoglycan DD-transpeptidase MrdA

研究结论

Date Results Publications
2020-02-08 11:50:00 mutations in PBP2 reduce susceptibility to carbapenems in E. coli clinical isolates that also have alterations of PBP3 and express the NDM-1 beta-lactamase 31270174
2013-08-31 12:02:00 Mutations in mreB, mrdA and mrdB suppress the shape defect of RodZ-deficient cells. 23301723
2010-01-21 00:00:00 Data show that MreB and FtsZ direct the synthesis of lateral cell wall via independent pathways that require PBP 2. 19346310
2010-01-21 00:00:00 The morphological effects and lysis were also eliminated entirely when overproduction of penicillin-binding protein 2 (PBP 2) and variants was conducted. 17513478
2010-01-21 00:00:00 Cells lacking mrdA were fully viable and propagated as small spheres under conditions of slow mass increase but formed large nondividing spheroids with noncanonical FtsZ assembly patterns at higher mass doubling rates. 17993535

名称对应

Type IDs
Synonymous ECK0628, pbpA
Gene
UniProtKB-ID: MRDA_ECOLI
UniprotKB: P0AD65
UniParc: UPI0000131389
EMBL: X04516, M22857, U00096, U82598, AP009048
EnsemblGenome: b0635, BAA35282
KO: eco:b0635, ecj:JW0630
Nucleutide sequences
EMBL-CDS: CAA28201.1, AAC73736.1, AAA24570.1, BAA35282.1, AAB40835.1
EnsemblGenome_TRS: BAA35282, AAC73736
Protein sequencees
EnsemblGenome_PRO: AAC73736, BAA35282
RefSeq: NP_415168.1
Others
UniRef100: UniRef100_P0AD67
UniRef90: UniRef90_P0AD67
UniRef50: UniRef50_P0AD67

全选

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研究热度

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