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945239 rlmH

945239

rlmH

23S rRNA m(3)psi1915 methyltransferase

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition 23S rRNA m(3)psi1915 methyltransferase

研究结论

Date Results Publications
2018-09-08 11:49:00 Data suggest that E. coli RlmH functions as a dimer, with the S-adenosyl-methionine binding pocket of one monomer and the C-terminal residues of its counterpart forming a composite active site. Study proposes that the C-terminal tail provides a residue that acts as a general base while the other conserved residues form a network of interactions that organize the catalytic site. 28428565
2012-08-04 11:22:00 While the synthesis of Psis in H69 by RluD is relatively insensitive to the point mutations at neighboring positions, methylation of one of the Psis by RlmH exhibited a much stronger sensitivity. 22586702
2010-11-27 10:33:00 show that RlmH has unique substrate specificity among rRNA modification enzymes 20817755
2010-01-21 00:00:00 E. coli protein YbeA as the methyltransferase methylating Psi1915 in 23S rRNA was identified. 18755836
2010-01-21 00:00:00 The identity of the methyltransferase YbeA (redesignated RlmH for rRNA large subunit methyltransferase H) that specifically catalyzes methyl group addition to form m(3)Psi1915 is reported. 18755835

名称对应

Type IDs
Synonymous ECK0629, ybeA
Gene
UniProtKB-ID: RLMH_ECOLI
UniprotKB: P0A8I8
UniParc: UPI000013A2FB
EMBL: X04516, AP009048, U82598, U00096
EnsemblGenome: b0636, BAA35283
KO: ecj:JW0631, eco:b0636
Nucleutide sequences
EMBL-CDS: BAA35283.1, AAB40836.1, AAC73737.1, CAA28200.1
EnsemblGenome_TRS: AAC73737, BAA35283
Protein sequencees
EnsemblGenome_PRO: BAA35283, AAC73737
RefSeq: NP_415169.1
Others
UniRef100: UniRef100_A7ZJ25
UniRef90: UniRef90_A8AJG7
UniRef50: UniRef50_Q3IJ98

全选

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