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945224 dsbG

945224

dsbG

protein sulfenic acid reductase DsbG

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition protein sulfenic acid reductase DsbG

研究结论

Date Results Publications
2019-09-21 11:48:00 We showed, for the first time, that the periplasmic protein DsbG has chaperone activity in vivo. 30012727
2017-04-15 10:13:00 By borrowing the CGPC active site of Trx-1 in combination with a T200M point mutation, we transformed DsbG into an enzyme highly reactive toward GSNO and YbiS. The pKa of the nucleophilic cysteine, as well as the redox and thermodynamic properties of the engineered DsbG are dramatically changed and become similar to those of Trx-1. 27226614
2016-02-06 10:09:00 Study isolated utilized a screen to isolate mutants of the sulfenic acid reductase (DsbG) that allowed this protein to act as a disulfide bond isomerase. 26191605
2010-01-21 00:00:00 study found that DsbG & DsbC control the global sulfenic acid content of the periplasm & protect single cysteine residues from oxidation; DsbG interacts with the YbiS protein and, along with DsbC, regulates oxidation of its catalytic cysteine residue 19965429
2010-01-21 00:00:00 Protein Disulfide-Isomerase 17609373

名称对应

Type IDs
Synonymous ECK0598, ybdP
Gene
UniProtKB-ID: DSBG_ECOLI
UniprotKB: P77202
UniParc: UPI00001298ED
EMBL: U00096, U82598, AP009048, AF000956
EnsemblGenome: BAA35234, b0604
KO: ecj:JW0597, eco:b0604
Nucleutide sequences
EMBL-CDS: AAB40805.1, AAC45785.1, BAA35234.2, AAC73705.2
EnsemblGenome_TRS: BAA35234, AAC73705
Protein sequencees
EnsemblGenome_PRO: AAC73705, BAA35234
RefSeq: NP_415137.2
Others
UniRef100: UniRef100_P77202
UniRef90: UniRef90_P77202
UniRef50: UniRef50_P77202

全选

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研究热度

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