| Type | Description |
|---|---|
| Definition | integral membrane protein 2A |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | GPR174 and ITM2A Gene Polymorphisms rs3827440 and rs5912838 on the X chromosome in Korean Children with Autoimmune Thyroid Disease. | 32727090 |
| 2020-09-12 11:05:00 | The ITM2A is a novel positive regulator of autophagy through an mTOR-dependent manner. | 31438969 |
| 2017-07-22 10:23:00 | ITM2A might be a susceptibility gene for Graves disease in the Xq21.1 locus, and environmental factors, such as viral and bacterial infections, probably contribute to GD pathogenesis by interacting with the risk SNP rs3827440 mediating the regulation of ITM2A expression. | 27809695 |
| 2016-07-02 10:14:00 | ITM2A is a new biomarker of poor prognosis in ovarian cancer and a novel tumor suppressor that induces cell cycle arrest, acts as a chemosensitizer, and has therapeutic potential for ovarian cancer. | 26691219 |
| 2016-03-26 10:26:00 | The upregulated gene with the largest effect size in ankylosing spondylitis was ITM2A, which plays a role in activation of T cells. (Meta-analysis) | 26125709 |
| Type | IDs |
|---|---|
| Synonymous | BRICD2A, E25A |
| Gene |
UniProtKB-ID:
ITM2A_HUMAN
UniprotKB:
O43736
UniParc:
UPI0000D9F4DB,
UPI000000D98A
EMBL:
AK303238,
AF038953,
AY359051,
AL021786,
CR456875,
AL009028,
BC040437,
CH471104,
AK313154
Ensembl:
ENSG00000078596
KO:
hsa:9452
|
| Nucleutide sequences |
EMBL-CDS:
AAC39867.1,
BAG64324.1,
AAH40437.1,
BAG35972.1,
CAG33156.1,
EAW98591.1,
AAQ89410.1
Gene_ORFName:
UNQ603/PRO1189
Ensembl_TRS:
ENST00000434584,
ENST00000373298
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362395,
ENSP00000415533
RefSeq:
NP_004858.1,
NP_001165052.1
|
| Others |
UniRef100:
UniRef100_O43736
UniRef90:
UniRef90_O43736
UniRef50:
UniRef50_O43736
UniGene:
Hs.17109,
Hs.694944
CCDS:
CCDS55455.1,
CCDS14444.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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