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945112 acrA

945112

acrA

multidrug efflux pump membrane fusion lipoprotein AcrA

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition multidrug efflux pump membrane fusion lipoprotein AcrA

研究结论

Date Results Publications
2020-10-24 14:04:00 Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold. 32032658
2020-07-11 10:46:00 AcrA, the membrane fusion protein, connects the inner-membrane-bound AcrB to the outer-membrane-bound TolC to form the multidrug efflux pump. 31517484
2019-12-21 10:15:00 In the presence of translation-inhibiting antibiotics, resistance acquisition depends on the AcrAB-TolC multidrug efflux pump, because it reduces tetracycline concentrations in the cell. 31123134
2018-08-11 10:17:00 It has been demonstrated that an intact AcrAB-TolC efflux pump is crucial to the development of bacterial quinolone resistance. Its activity is complemented by expression of the alternative AcrEF efflux pump. 28520511
2018-02-03 11:45:00 Ten phosphorus ylides were compared in multidrug efflux pump system consisting of the subunits acridine-resistance proteins A and B (AcrA and AcrB) and the multidrug efflux pump outer membrane factor TolC (TolC) and in AcrAB-TolC-deletion. 27815466

名称对应

Type IDs
Synonymous ECK0457, Mb, lir, mbl, mtcA, nbsA, sipB
Gene
UniProtKB-ID: ACRA_ECOLI
UniprotKB: P0AE06
UniParc: UPI0000125396
EMBL: M94248, U82664, AP009048, U00734, U00096
EnsemblGenome: b0463, BAE76242
KO: eco:b0463, ecj:JW0452
Nucleutide sequences
EMBL-CDS: BAE76242.1, AAA67134.1, AAB40217.1, AAC73565.1, AAA23410.1
EnsemblGenome_TRS: AAC73565, BAE76242
Protein sequencees
EnsemblGenome_PRO: BAE76242, AAC73565
RefSeq: NP_414996.1
Others
UniRef100: UniRef100_P0AE07
UniRef90: UniRef90_P0AE07
UniRef50: UniRef50_P24180

全选

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