Type | Description |
---|---|
Definition | multidrug efflux pump membrane fusion lipoprotein AcrA |
Date | Results | Publications |
---|---|---|
2020-10-24 14:04:00 | Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold. | 32032658 |
2020-07-11 10:46:00 | AcrA, the membrane fusion protein, connects the inner-membrane-bound AcrB to the outer-membrane-bound TolC to form the multidrug efflux pump. | 31517484 |
2019-12-21 10:15:00 | In the presence of translation-inhibiting antibiotics, resistance acquisition depends on the AcrAB-TolC multidrug efflux pump, because it reduces tetracycline concentrations in the cell. | 31123134 |
2018-08-11 10:17:00 | It has been demonstrated that an intact AcrAB-TolC efflux pump is crucial to the development of bacterial quinolone resistance. Its activity is complemented by expression of the alternative AcrEF efflux pump. | 28520511 |
2018-02-03 11:45:00 | Ten phosphorus ylides were compared in multidrug efflux pump system consisting of the subunits acridine-resistance proteins A and B (AcrA and AcrB) and the multidrug efflux pump outer membrane factor TolC (TolC) and in AcrAB-TolC-deletion. | 27815466 |
Type | IDs |
---|---|
Synonymous | ECK0457, Mb, lir, mbl, mtcA, nbsA, sipB |
Gene |
UniProtKB-ID:
ACRA_ECOLI
UniprotKB:
P0AE06
UniParc:
UPI0000125396
EMBL:
M94248,
U82664,
AP009048,
U00734,
U00096
EnsemblGenome:
b0463,
BAE76242
KO:
eco:b0463,
ecj:JW0452
|
Nucleutide sequences |
EMBL-CDS:
BAE76242.1,
AAA67134.1,
AAB40217.1,
AAC73565.1,
AAA23410.1
EnsemblGenome_TRS:
AAC73565,
BAE76242
|
Protein sequencees |
EnsemblGenome_PRO:
BAE76242,
AAC73565
RefSeq:
NP_414996.1
|
Others |
UniRef100:
UniRef100_P0AE07
UniRef90:
UniRef90_P0AE07
UniRef50:
UniRef50_P24180
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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