| Type | Description |
|---|---|
| Definition | multidrug efflux pump RND permease AcrB |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:31:00 | Substrate-dependent transport mechanism in AcrB of multidrug resistant bacteria. | 31998988 |
| 2020-10-24 14:04:00 | Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold. | 32032658 |
| 2020-10-03 12:59:00 | Cryo-EM analysis of a membrane protein embedded in the liposome. | 32680969 |
| 2020-07-11 10:46:00 | AcrA, the membrane fusion protein, connects the inner-membrane-bound AcrB to the outer-membrane-bound TolC to form the multidrug efflux pump. | 31517484 |
| 2019-12-21 10:15:00 | In the presence of translation-inhibiting antibiotics, resistance acquisition depends on the AcrAB-TolC multidrug efflux pump, because it reduces tetracycline concentrations in the cell. | 31123134 |
| Type | IDs |
|---|---|
| Synonymous | ECK0456, acrE |
| Gene |
UniProtKB-ID:
ACRB_ECOLI
UniprotKB:
P31224
UniParc:
UPI0000125397
EMBL:
M94248,
U82664,
U00734,
AP009048,
U00096
EnsemblGenome:
b0462,
BAE76241
KO:
ecj:JW0451,
eco:b0462
|
| Nucleutide sequences |
EMBL-CDS:
AAB40216.1,
AAC73564.1,
AAA23411.1,
BAE76241.1,
AAA67135.1
EnsemblGenome_TRS:
AAC73564,
BAE76241
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC73564,
BAE76241
RefSeq:
NP_414995.1
|
| Others |
UniRef100:
UniRef100_P31224
UniRef90:
UniRef90_P31224
UniRef50:
UniRef50_P31224
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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