| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 2 alpha kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:13:00 | AGEs exacerbates coronary microvascular dysfunction in NoCAD by activating endoplasmic reticulum stress-mediated PERK signaling pathway. | 33485865 |
| 2021-04-03 13:34:00 | COG5 variants lead to complex early onset retinal degeneration, upregulation of PERK and DNA damage. | 33277529 |
| 2021-03-13 13:25:00 | Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma. | 31691973 |
| 2021-01-30 13:02:00 | Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma. | 31869409 |
| 2021-01-02 12:49:00 | The kinase PERK represses translation of the G-protein-coupled receptor LGR5 and receptor tyrosine kinase ERBB3 during ER stress in cancer cells. | 32107308 |
| Type | IDs |
|---|---|
| Synonymous | PEK, PERK, WRS |
| Gene |
UniProtKB-ID:
E2AK3_HUMAN,
B3KY45_HUMAN,
Q68DI6_HUMAN
UniprotKB:
Q9NZJ5,
B3KY45,
Q68DI6
UniParc:
UPI00004A29B7,
UPI000041A0F7,
UPI000013E87D
EMBL:
AF284615,
AF284608,
BC126354,
AF284612,
AF284613,
AF284614,
AF284609,
AK128659,
AF284605,
AF110146,
AF284607,
AF284610,
CR749382,
AC104134,
AF193339,
AF284604,
AK315287,
AF284606,
BC126356,
AF284611,
AC062029
Ensembl:
ENSG00000172071
KO:
hsa:9451
|
| Nucleutide sequences |
EMBL-CDS:
AAY14777.1,
AAF91480.1,
AAY24331.1,
AAF61199.1,
AAI26355.1,
AAI26357.1,
AAD19961.1,
BAG37696.1,
BAG54707.1,
CAH18234.1
Ensembl_TRS:
ENST00000303236
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307235
RefSeq:
XP_016860865.1,
NP_004827.4,
NP_001300844.1
|
| Others |
UniRef100:
UniRef100_Q68DI6,
UniRef100_Q9NZJ5,
UniRef100_B3KY45
UniRef90:
UniRef90_Q9NZJ5
UniRef50:
UniRef50_Q9Z2B5
UniGene:
Hs.591589
CCDS:
CCDS33241.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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