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945087 glnK

945087

glnK

nitrogen regulator GlnK

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition nitrogen regulator GlnK

研究结论

Date Results Publications
2017-08-12 10:14:00 Results show that GlnK is tightly regulated under nitrogen-rich conditions, yet it is expressed during ammonium run-out and starvation. This suggests a role for GlnK as a buffer of nitrogen shock after starvation, and provides a further functional link between nitrogen and carbon metabolisms. 28538158
2013-11-16 10:04:00 Data show that the P(II) protein, GlnK, has an ATPase activity that is inhibited by 2-oxoglutarate. 23818625
2011-03-19 11:00:00 Studies suggest a hypothesise that the regulatory protein GlnK is required to fine-tune the active transport of ammonium in order to limit futile cycling whilst enabling an intracellular ammonium level sufficient for the cell's nitrogen requirements. 21134373
2010-01-21 00:00:00 The GlnK protein binding causes a significant downshift in the Am6 pK(a) value of the AmtB. However, this downshift is perfectly compensated by the reorientation of the protein backbone upon AmtB-GlnK complex formation. 17707821
2010-01-21 00:00:00 GlnK interacts with AmtB almost exclusively via a long surface loop containing Y51 (T-loop), the tip of which inserts deeply into the cytoplasmic pore exit, blocking ammonia conduction 17220269

名称对应

Type IDs
Synonymous ECK0444, ybaI
Gene
UniProtKB-ID: GLNK_ECOLI
UniprotKB: P0AC55
UniParc: UPI0000111973
EMBL: AP009048, U00096, U40429, U82664, S79842
EnsemblGenome: BAE76230, b0450
KO: ecj:JW0440, eco:b0450
Nucleutide sequences
EMBL-CDS: AAD14836.1, AAC73553.1, BAE76230.1, AAB40206.1, AAA87955.1
EnsemblGenome_TRS: BAE76230, AAC73553
Protein sequencees
EnsemblGenome_PRO: AAC73553, BAE76230
RefSeq: NP_414984.1
Others
UniRef100: UniRef100_P0AC57
UniRef90: UniRef90_P0AC57
UniRef50: UniRef50_P0AC57

全选

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