panE - 2-dehydropantoate 2-reductase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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945065 panE

基因描述

Type	Description
Definition	2-dehydropantoate 2-reductase

研究结论

Date	Results	Publications
2010-01-21 00:00:00	analysis of the roles of active site residues of ketopantoate reductase and its conformational changes in substrate recognition and catalysis	17229734
2010-01-21 00:00:00	crystal structure of Escherichia coli ketopantoate reductase in complex with 2'-monophosphoadenosine 5'-diphosphoribose; binding changes with pH and mutations	17242510
2010-01-21 00:00:00	crystal structure of Escherichia coli KPR with NADP(+) bound, solved to 2.1 A resolution	15966718

名称对应

Type	IDs
Synonymous	ECK0419, apbA
Gene	UniProtKB-ID: PANE_ECOLI UniprotKB: P0A9J4 UniParc: UPI00001312D1 EMBL: U82664, U00096, U34923, AP009048 EnsemblGenome: b0425, BAE76205 KO: eco:b0425, ecj:JW0415
Nucleutide sequences	EMBL-CDS: AAA82703.1, AAC73528.1, BAE76205.1, AAB40181.1 EnsemblGenome_TRS: AAC73528, BAE76205
Protein sequencees	EnsemblGenome_PRO: BAE76205, AAC73528 RefSeq: NP_414959.1
Others	UniRef100: UniRef100_P0A9J4 UniRef90: UniRef90_P0A9J4 UniRef50: UniRef50_P0A9J4

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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全选

Pubmed编号	文献信息	发表日期	相关基因
24561554	The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. Seesandra V Rajagopala , Patricia Sikorski , Ashwani Kumar , Roberto Mosca , James Vlasblom , Roland Arnold , Jonathan Franca-Koh , Suman B Pakala , Sadhna Phanse , Arnaud Ceol , Roman HÃ¤user , Gabriella Siszler , Stefan Wuchty , Andrew Emili , Mohan Babu , Patrick Aloy , Rembert Pieper , Peter Uetz	2014-03-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19636932	Backbone assignments of the 34 kDa ketopantoate reductase from E. coli. Biomol NMR Assign Stephen J Headey , Amelia Vom , Jamie S Simpson , Martin J Scanlon	2008-06-01	panE
17305325	Identification of hot spots within druggable binding regions by computational solvent mapping of proteins. J. Med. Chem. Melissa R Landon , David R Lancia , Jessamin Yu , Spencer C Thiel , Sandor Vajda	2007-03-22	panE
17229734	Crystal structure of Escherichia coli ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change, and cooperativity. J Biol Chem Alessio Ciulli , Dimitri Y Chirgadze , Alison G Smith , Tom L Blundell , Chris Abell	2007-03-16	-
17242510	pH-tuneable binding of 2'-phospho-ADP-ribose to ketopantoate reductase: a structural and calorimetric study. Acta Crystallogr D Biol Crystallogr Alessio Ciulli , Carina M C Lobley , Kellie L Tuck , Alison G Smith , Tom L Blundell , Chris Abell	2007-02-01	-
16884311	Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods. J. Med. Chem. Alessio Ciulli , Glyn Williams , Alison G Smith , Tom L Blundell , Chris Abell	2006-08-10	-
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
15966718	The crystal structure of Escherichia coli ketopantoate reductase with NADP+ bound. Biochemistry Carina M C Lobley , Alessio Ciulli , Heather M Whitney , Glyn Williams , Alison G Smith , Chris Abell , Tom L Blundell	2005-06-28	panE

研究热度

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