| Type | Description |
|---|---|
| Definition | DNA-binding transcriptional repressor LacI |
| Date | Results | Publications |
|---|---|---|
| 2016-08-06 10:16:00 | Effect of helix length on the stability of the Lac repressor antiparallel coiled coil. | 25969365 |
| 2013-09-21 13:21:00 | LacI autoregulation balances two opposing states, one that allows quicker response to smaller pulses of external lactose, and the other that minimizes production costs in the absence of lactose. | 23658223 |
| 2012-10-13 11:32:00 | Data indicate that in the absence of its inducer, LacI binds to primary operator lac O1 near the transcription start site of the lac operon, and represses its transcription. | 22594825 |
| 2012-07-21 10:23:00 | findings show the lac repressor slides 45 +/- 10 base pairs on chromosomal DNA and that sliding can be obstructed by other DNA-bound proteins near the operator; the repressor frequently slides over its natural lacO(1) operator several times before binding | 22723426 |
| 2011-12-10 11:19:00 | The role of lactose repressor residues asparagine-125 and aspartate-149 illustrate how readily the ligand binding and allosteric response function of a regulatory bacterial protein can be altered, generating diminished operator binding. | 21928765 |
| Type | IDs |
|---|---|
| Synonymous | ECK0342 |
| Gene |
UniProtKB-ID:
LACI_ECOLI,
A0A4D6FVL5_ECOLI
UniprotKB:
P03023,
A0A4D6FVL5
UniParc:
UPI000011D868
EMBL:
U72488,
J01636,
U00096,
U86347,
U78873,
U78872,
U78874,
MK753226,
U73857,
AP009048,
X58469,
V00294,
MK753228
EnsemblGenome:
BAE76127,
b0345
KO:
ecj:JW0336,
eco:b0345
|
| Nucleutide sequences |
EMBL-CDS:
CAA23569.1,
AAC73448.1,
BAE76127.1,
AAB47270.1,
CAA41383.1,
AAB37354.1,
AAB36549.1,
AAA24052.1,
AAB37348.1,
AAB37351.1,
AAB18069.1,
QCB65867.1,
QCB65859.1
EnsemblGenome_TRS:
AAC73448,
BAE76127
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE76127,
AAC73448
RefSeq:
NP_414879.3
|
| Others |
UniRef100:
UniRef100_P03023
UniRef90:
UniRef90_P03023
UniRef50:
UniRef50_P03023
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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