A reference map of the human binary protein interactome.

Nature     Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat Taşan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood

Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response.

PLoS Pathog     Dylan H de Vries , Vasiliki Matzaraki , Olivier B Bakker , Harm Brugge , Harm-Jan Westra , Mihai G Netea , Lude Franke , Vinod Kumar , Monique G P van der Wijst

MD-1 deficiency attenuates dextran sodium sulfate (DSS)-induced colitis through modulating the function of colonic lamina propria dendritic cells.

Mol. Immunol.     Huaqin Pan , Guqin Zhang , Lin Zhang , Wei Wang , Jian Shang , Xiaobing Wang , Qiu Zhao , Jin Li

DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation.

Twin Res Hum Genet     Shaoyong Su , Haidong Zhu , Xiaojing Xu , Xin Wang , Yanbin Dong , Gaston Kapuku , Frank Treiber , Bernard Gutin , Gregory Harshfield , Harold Snieder , Xiaoling Wang

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

Nat. 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Genome-wide association of body fat distribution in African ancestry populations suggests new loci.

PLoS Genet     Ching-Ti Liu , Keri L Monda , Kira C Taylor , Leslie Lange , Ellen W Demerath , Walter Palmas , Mary K Wojczynski , Jaclyn C Ellis , Mara Z Vitolins , Simin Liu , George J Papanicolaou , Marguerite R Irvin , Luting Xue , Paula J Griffin , Michael A Nalls , Adebowale Adeyemo , Jiankang Liu , Guo Li , Edward A Ruiz-Narvaez , Wei-Min Chen , Fang Chen , Brian E Henderson , Robert C Millikan , Christine B Ambrosone , Sara S Strom , Xiuqing Guo , Jeanette S Andrews , Yan V Sun , Thomas H Mosley , Lisa R Yanek , Daniel Shriner , Talin Haritunians , Jerome I Rotter , Elizabeth K Speliotes , Megan Smith , Lynn Rosenberg , Josyf Mychaleckyj , Uma Nayak , Ida Spruill , W Timothy Garvey , Curtis Pettaway , Sarah Nyante , Elisa V Bandera , Angela F Britton , Alan B Zonderman , Laura J Rasmussen-Torvik , Yii-Der Ida Chen , Jingzhong Ding , Kurt Lohman , Stephen B Kritchevsky , Wei Zhao , Patricia A Peyser , Sharon L R Kardia , Edmond Kabagambe , Ulrich Broeckel , Guanjie Chen , Jie Zhou , Sylvia Wassertheil-Smoller , Marian L Neuhouser , Evadnie Rampersaud , Bruce Psaty , Charles Kooperberg , Joann E Manson , Lewis H Kuller , Heather M Ochs-Balcom , Karen C Johnson , Lara Sucheston , Jose M Ordovas , Julie R Palmer , Christopher A Haiman , Barbara McKnight , Barbara V Howard , Diane M Becker , Lawrence F Bielak , Yongmei Liu , Matthew A Allison , Struan F A Grant , Gregory L Burke , Sanjay R Patel , Pamela J Schreiner , Ingrid B Borecki , Michele K Evans , Herman Taylor , Michele M Sale , Virginia Howard , Christopher S Carlson , Charles N Rotimi , Mary Cushman , Tamara B Harris , Alexander P Reiner , L Adrienne Cupples , Kari E North , Caroline S Fox

Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family.

J. Mol. Biol.     Umeharu Ohto , Kensuke Miyake , Toshiyuki Shimizu

Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein.

J Biol Chem     Judit Oláh , Orsolya Vincze , Dezsõ Virók , Dóra Simon , Zsolt Bozsó , Natália Tõkési , István Horváth , Emma Hlavanda , János Kovács , Anna Magyar , Mária SzÅ©cs , Ferenc Orosz , Botond Penke , Judit Ovádi

An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1.

Nat. Struct. Mol. Biol.     Sung-il Yoon , Minsun Hong , Ian A Wilson

LPS ligand and culture additives improve production of monomeric MD-1 and 2 in Pichia pastoris by decreasing aggregation and intermolecular disulfide bonding.

Protein Expr Purif     Kristen E Mengwasser , Clare E Bryant , Nick J Gay , Monique Gangloff