| Type | Description |
|---|---|
| Definition | 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | A catalytic mechanism is proposed involving stabilisation of reactive intermediates and activation of a nucleophilic water molecule by Ser110 | 15663941 |
| 2010-01-21 00:00:00 | Replacement of Arg-188 in MhpC with Gln and Lys led to 200- and 40-fold decreases, respectively, in k(cat). | 17029402 |
| 2010-01-21 00:00:00 | X ray structure | 15663942 |
| 2010-01-21 00:00:00 | A new line-broadened signal was observed upon incubation of the (13)C-labeled substrate with an H114A MhpC mutant, which is able to accept the 6-phenyl-containing substrate, on a shorter time scale. | 17029401 |
| Type | IDs |
|---|---|
| Synonymous | ECK0346 |
| Gene |
UniProtKB-ID:
MHPC_ECOLI
UniprotKB:
P77044
UniParc:
UPI0001B525AB
EMBL:
U73857,
AP009048,
U00096,
Y09555,
D86239
EnsemblGenome:
b0349,
BAE76131
KO:
ecj:JW0340,
eco:b0349
|
| Nucleutide sequences |
EMBL-CDS:
AAC73452.3,
BAA13054.1,
AAB18073.1,
CAA70749.1,
BAE76131.1
EnsemblGenome_TRS:
AAC73452,
BAE76131
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE76131,
AAC73452
RefSeq:
NP_414883.5
|
| Others |
UniRef100:
UniRef100_B1XBJ6
UniRef90:
UniRef90_Q8X5K0
UniRef50:
UniRef50_P47229
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 17029402 |
Biochemistry Chen Li , Jian-Jun Li , Mark G Montgomery , Stephen P Wood , Timothy D H Bugg |
2006-10-17 |
BXE_RS42260,
mhpC
|
| 17029401 |
Biochemistry Jian-Jun Li , Chen Li , Claudia A Blindauer , Timothy D H Bugg |
2006-10-17 |
BXE_RS42260,
mhpC
|
| 16738553 |
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi |
2006-01-01 |
pmrR,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeB,
yohO,
arnE,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
wecF,
yigE,
blr,
yggP,
cpxP,
hdfR,
thiS,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
yhaM,
tdcG,
ytfR,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yneM,
ykfM,
ylcI,
yciY,
yncL,
ylcH,
ynhF,
yciZ,
ydgU,
ypfM,
ymgI,
ymgJ,
dinQ
|
| 16381862 |
MEROPS: the peptidase database. Nucleic Acids Res. Neil D Rawlings , Fraser R Morton , Alan J Barrett |
2006-01-01 |
yghX,
lspA,
rseP,
yafL,
yafJ,
mhpC,
hypF,
yahJ,
frmB,
codA,
pepD,
yfhR,
yajL,
clpP,
lon,
trpD,
allB,
allC,
loiP,
ompT,
mepH,
dacA,
asnB,
ybfF,
nagA,
dacC,
iaaA,
ddpX,
ycaL,
ycbK,
ycbZ,
hyaD,
cohE,
abgA,
umuD,
ldcA,
pyrC,
yfbL,
sohB,
puuD,
abgB,
mpaA,
ynbC,
ycjY,
ydcP,
pqqL,
htpX,
dcp,
prc,
pyrG,
nlpC,
sppA,
tsaB,
pepT,
ptrB,
mepM,
ydgD,
hchA,
dacD,
rutD,
yegQ,
pbpG,
mepS,
menH,
elaD,
purF,
mepA,
ypdE,
ypdF,
ampH,
yfeW,
nlpD,
bepA,
lepB,
degP,
iap,
pepN,
ptrA,
guaA,
ygeR,
hyuA,
ygeY,
guaD,
pepP,
hycI,
pppA,
aes,
tsaD,
agaA,
yhbO,
ftsH,
dacB,
gltB,
tldD,
degQ,
gspO,
yheT,
degS,
pabA
|
| 16397293 |
Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner |
2006-01-01 |
pmrR,
yfaS,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeF,
yoeB,
yohO,
arnE,
ypdJ,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
yifN,
wecF,
yigE,
blr,
yggP,
cpxP,
ygaY,
hdfR,
thiS,
yedN,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
glvC,
yhaM,
tdcG,
ytfR,
yehH,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
gapC,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
yedS,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yaiX,
yoeA,
yneM
|
| 9603882 |
J. Bacteriol. E DÃaz , A Ferrández , J L GarcÃa |
1998-06-01 |
ECs3406,
mhpD,
mhpC,
mhpT,
mhpF,
mhpE,
mhpB,
mhpA,
hcaB,
hcaD,
mhpR,
hcaF,
hcaE,
hcaR,
hcaT,
hcaC,
yphA
|
| 9315862 |
Biochemistry W W Lam , T D Bugg |
1997-10-07 | - |
| 9278503 |
The complete genome sequence of Escherichia coli K-12. Science F R Blattner , G Plunkett , C A Bloch , N T Perna , V Burland , M Riley , J Collado-Vides , J D Glasner , C K Rode , G F Mayhew , J Gregor , N W Davis , H A Kirkpatrick , M A Goeden , D J Rose , B Mau , Y Shao |
1997-09-05 | - |
| 9098055 |
J. Bacteriol. A Ferrández , J L Garciá , E DÃaz |
1997-04-01 | - |
| 8399388 |
Biochim. Biophys. Acta T D Bugg |
1993-10-06 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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