rseP - intramembrane zinc metalloprotease-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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944871 rseP

基因描述

Type	Description
Definition	intramembrane zinc metalloprotease

研究结论

Date	Results	Publications
2020-12-26 13:15:00	Instability of CII is needed for efficient switching between lytic and lysogenic development in bacteriophage 186.	33211866
2017-08-19 11:15:00	we describe several methods for characterization of the proteolytic functions and structure of RseP mainly in vivo, including a proteolytic activity assay using model substrates, an in vitro analysis of cleavage of signal peptides in a detergent solution and in the membrane vesicles, structural analysis of membrane-embedded RseP based on the thiol modifiability of introduced cysteine residues, and the protein interaction	28065260
2016-07-02 10:37:00	Mutations disturbing the possible beta-strand conformation of the loop impaired RseP proteolytic activity and that some of these mutations resulted in the differential cleavage of different substrates.	26447507
2013-05-25 11:09:00	study concludes that recognition of the cleaved amino acid by the RseP PDZ domain is not essential for sequential cleavage of RseA and sigma(E) stress response in vivo	23016873
2011-11-26 10:36:00	Escherichia coli RseP, an site-2 protease (S2P) family I-CLiP, introduces a cleavage into signal peptides after their signal peptidase-mediated liberation from preproteins	21810987

名称对应

Type	IDs
Synonymous	ECK0175, ecfE, yaeL
Gene	UniProtKB-ID: RSEP_ECOLI UniprotKB: P0AEH1 UniParc: UPI0000032C9E EMBL: M11330, AF407012, AP009048, U00096, U70214 EnsemblGenome: b0176, BAA77851 KO: ecj:JW0171, eco:b0176
Nucleutide sequences	EMBL-CDS: AAB08605.1, BAA77851.1, AAC73287.1, AAL01378.1 EnsemblGenome_TRS: BAA77851, AAC73287
Protein sequencees	EnsemblGenome_PRO: AAC73287, BAA77851 RefSeq: NP_414718.1
Others	UniRef100: UniRef100_P0AEH2 UniRef90: UniRef90_P0AEH2 UniRef50: UniRef50_D0ZKX9

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
33211866	Instability of CII is needed for efficient switching between lytic and lysogenic development in bacteriophage 186. Nucleic Acids Res Iain M Murchland , Alexandra Ahlgren-Berg , Julian M J Pietsch , Alejandra Isabel , Ian B Dodd , Keith E Shearwin	2020-12-02	-
28065260	Biochemical Characterization of Function and Structure of RseP, an Escherichia coli S2P Protease. Meth. Enzymol. Y Hizukuri , K Akiyama , Y Akiyama	2017-01-01	-
26447507	Roles of the membrane-reentrant Î²-hairpin-like loop of RseP protease in selective substrate cleavage. Elife Koichiro Akiyama , Shinya Mizuno , Yohei Hizukuri , Hiroyuki Mori , Terukazu Nogi , Yoshinori Akiyama	2015-01-01	-
23016873	PDZ domains of RseP are not essential for sequential cleavage of RseA or stress-induced Ï(E) activation in vivo. Mol. Microbiol. Yohei Hizukuri , Yoshinori Akiyama	2012-12-01	rseP, rpoE, rseA
21810987	Post-liberation cleavage of signal peptides is catalyzed by the site-2 protease (S2P) in bacteria. Proc. Natl. Acad. Sci. U.S.A. Akira Saito , Yohei Hizukuri , Ei-ichi Matsuo , Shinobu Chiba , Hiroyuki Mori , Osamu Nishimura , Koreaki Ito , Yoshinori Akiyama	2011-08-16	rseP
19706448	Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage. Proc Natl Acad Sci U S A Xiaochun Li , Boyuan Wang , Lihui Feng , Hui Kang , Yang Qi , Jiawei Wang , Yigong Shi	2009-09-01	-
19717451	Rip exposed: how ectodomain shedding regulates the proteolytic processing of transmembrane substrates. Proc. Natl. Acad. Sci. U.S.A. Daniel R Dries , Gang Yu	2009-09-01	rseP, rpoE, rseA, degS
19144914	Regulation of ribonuclease E activity by the L4 ribosomal protein of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. Dharam Singh , Ssu-Jean Chang , Pei-Hsun Lin , Olga V Averina , Vladimir R Kaberdin , Sue Lin-Chao	2009-01-20	rseP, lon, cstA, rne, hslO, rplD, yjiY
18945679	A pair of circularly permutated PDZ domains control RseP, the S2P family intramembrane protease of Escherichia coli. J Biol Chem Kenji Inaba , Mamoru Suzuki , Ken-ichi Maegawa , Shuji Akiyama , Koreaki Ito , Yoshinori Akiyama	2008-12-12	-
18268014	Substrate recognition and binding by RseP, an Escherichia coli intramembrane protease. J Biol Chem Kayo Koide , Koreaki Ito , Yoshinori Akiyama	2008-04-11	-

研究热度

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