lpd - lipoamide dehydrogenase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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944854 lpd

基因描述

Type	Description
Definition	lipoamide dehydrogenase

研究结论

Date	Results	Publications
2012-09-22 10:50:00	Glutamate at position 354 plays a structural role in establishing the NADH sensitivity of LPD and the PDH complex by lowering the affinity for NADH.	22343352
2010-01-21 00:00:00	results show that a mutation in LPD led to a pyruvate dehydrogenase complex that is less sensitive to inhibition by NADH	18375566
2007-11-05 21:38:00	N-terminus verified by Edman degradation on mature peptide	6352260,9298646

名称对应

Type	IDs
Synonymous	ECK0115, dhl, lpdA
Gene	UniProtKB-ID: DLDH_ECOLI UniprotKB: P0A9P0 UniParc: UPI000016539B EMBL: V01498, U00096, AP009048 EnsemblGenome: b0116, BAB96686 KO: ecj:JW0112, eco:b0116
Nucleutide sequences	EMBL-CDS: CAA24742.1, BAB96686.2, AAC73227.1 EnsemblGenome_TRS: BAB96686, AAC73227
Protein sequencees	EnsemblGenome_PRO: BAB96686, AAC73227 RefSeq: NP_414658.1
Others	UniRef100: UniRef100_P0A9P2 UniRef90: UniRef90_P0A9P2 UniRef50: UniRef50_P0A9P2

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
24561554	The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. Seesandra V Rajagopala , Patricia Sikorski , Ashwani Kumar , Roberto Mosca , James Vlasblom , Roland Arnold , Jonathan Franca-Koh , Suman B Pakala , Sadhna Phanse , Arnaud Ceol , Roman HÃ¤user , Gabriella Siszler , Stefan Wuchty , Andrew Emili , Mohan Babu , Patrick Aloy , Rembert Pieper , Peter Uetz	2014-03-01	-
24580753	Inferring gene function from evolutionary change in signatures of translation efficiency. Genome Biol. Anita Krisko , Tea Copic , Toni GabaldÃ³n , Ben Lehner , Fran Supek	2014-01-01	-
22343352	Amino acid substitutions at glutamate-354 in dihydrolipoamide dehydrogenase of Escherichia coli lower the sensitivity of pyruvate dehydrogenase to NADH. Microbiology (Reading, Engl.) Zhentao Sun , Phi Minh Do , Mun Su Rhee , Lakshmanan Govindasamy , Qingzhao Wang , Lonnie O Ingram , K T Shanmugam	2012-05-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18852508	The diversity of lysine-acetylated proteins in Escherichia coli. J. Microbiol. Biotechnol. Byung Jo Yu , Jung Ae Kim , Jeong Hee Moon , Seong Eon Ryu , Jae-Gu Pan	2008-09-01	sslE, talB, dnaK, carB, aceF, lpd, dapD, acnB, tsf, pepD, eno, gpmA, tig, htpG, serA, fldA, sucB, sucD, gltA, rpsA, cobB, icd, prs, kdsA, purU, adhE, topA, tpx, pyrG, grxD, aspS, motB, yeeN, cysK, crr, rimJ, cysS, guaB, pka, grpE, recA, pgk, tktA, ahpF, rpoD, fadH, pnp, gapA, ftsH, glmM, nanA, rplQ, rpsK, rpsD, rpoA, rplE, rplD, tufA, fusA, mdh, crp, rpsB, asd, cysE, tnaA, atpD, rho, sodA, tufB, rplA, aceA, pgi, ssb, acs, groL, rplI, rpsR, rpsF, ppa, pyrB, pepA, tsr, guaC, folE
18375566	Dihydrolipoamide dehydrogenase mutation alters the NADH sensitivity of pyruvate dehydrogenase complex of Escherichia coli K-12. J. Bacteriol. Youngnyun Kim , L O Ingram , K T Shanmugam	2008-06-01	lpd
18304323	Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics Yasushi Ishihama , Thorsten Schmidt , Juri Rappsilber , Matthias Mann , F Ulrich Hartl , Michael J Kerner , Dmitrij Frishman	2008-01-01	-
18941301	Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia. Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. Goro Kikuchi , Yutaro Motokawa , Tadashi Yoshida , Koichi Hiraga	2008-01-01	-
17698812	Metabolite essentiality elucidates robustness of Escherichia coli metabolism. Proc. Natl. Acad. Sci. U.S.A. Pan-Jun Kim , Dong-Yup Lee , Tae Yong Kim , Kwang Ho Lee , Hawoong Jeong , Sang Yup Lee , Sunwon Park	2007-08-21	lpd, dxs, purN, glyA, xylB
17122336	Genome-wide screening of genes required for swarming motility in Escherichia coli K-12. J. Bacteriol. Tetsuyoshi Inoue , Ryuji Shingaki , Shotaro Hirose , Kaori Waki , Hirotada Mori , Kazuhiro Fukui	2007-02-01	wecF, gapC, ydbA, ygaQ, dnaK, wecB, mrcB, lpd, skp, argP, gmhB, hscA, rof, galM, cusR, pal, tusE, yaiW, cvpA, cyoA, htpG, dps, ninE, purK, fes, entF, fepA, fepG, ybdH, fepD, ybdO, ybeD, lipA, ubiF, pgm, asnB, nagC, sdhB, sucA, sucB, sucD, sdhC, tolR, sapF, arnF, galE, sdhA, yqaA, ybiA, tolB, cmk, ompA, mgsA, hspQ, hyaA, hyaB, ycdY, ndk, flgN, flgE, ynfG, flgF, flgL, flgG, flgK, aldA, flgB, ymfA, hflD, galU, cvrA, treA, cysB, narH, chaC, ppdC, oppC, flgD, fucU, ogt, rssB, trpL, osmB, gmr, ycjW, tpx, ydaT, pgrR, prpD, ydcX, mpaA, hicA, fabH, ydcZ, yncH, osmC, ppiD, hipB, htpX

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