rnhB - RNase HII-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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944852 rnhB

基因描述

Type	Description
Definition	RNase HII

研究结论

Date	Results	Publications
2017-10-07 10:05:00	The authors propose that RNase H-deficient mutants convert some R-loops into R-tracts, which progress into R-gaps and then to double-strand breaks-explaining why R-tracts do not accumulate in RNase H-deficient cells, while double-strand breaks do.	28821455
2010-01-21 00:00:00	The data suggest a requirement for ionisation of an active site carboxylic acid for metal ion binding or correct positioning of metal ion(s) in the enzyme-substrate complex and a role for a second active site carboxylate in general base catalysis.	17355881
2007-11-05 21:38:00	N-terminus verified by Edman degradation on complete protein	2172991

名称对应

Type	IDs
Synonymous	ECK0182
Gene	UniProtKB-ID: RNH2_ECOLI UniprotKB: P10442 UniParc: UPI00001343C4 EMBL: AP009048, M19334, U00096, U70214 EnsemblGenome: BAA77858, b0183 KO: ecj:JW0178, eco:b0183
Nucleutide sequences	EMBL-CDS: AAC73294.1, AAB08612.1, BAA77858.2 EnsemblGenome_TRS: BAA77858, AAC73294
Protein sequencees	EnsemblGenome_PRO: BAA77858, AAC73294 RefSeq: NP_414725.1
Others	UniRef100: UniRef100_A7ZHS3 UniRef90: UniRef90_Q8X8X6 UniRef50: UniRef50_Q9HXY9

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
28821455	RNase HII Saves rnhA Mutant Escherichia coli from R-Loop-Associated Chromosomal Fragmentation. J. Mol. Biol. Elena A Kouzminova , Farid F Kadyrov , Andrei Kuzminov	2017-09-15	-
23144626	Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol V. PLoS Genet John P McDonald , Alexandra Vaisman , Wojciech Kuban , Myron F Goodman , Roger Woodgate	2012-01-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19228197	Ribonuclease H: molecular diversities, substrate binding domains, and catalytic mechanism of the prokaryotic enzymes. FEBS J. Takashi Tadokoro , Shigenori Kanaya	2009-03-01	rnhB, rnhA
17355881	The pH-dependence of the Escherichia coli RNase HII-catalysed reaction suggests that an active site carboxylate group participates directly in catalysis. J. Mol. Biol. James A Bastock , Michelle Webb , Jane A Grasby	2007-04-27	rnhB
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
16336047	Conserved and variable functions of the sigmaE stress response in related genomes. PLoS Biol. Virgil A Rhodius , Won Chul Suh , Gen Nonaka , Joyce West , Carol A Gross	2006-01-01	lpxB, lpxA, rnhB, skp, bamA, dnaE, lpxD, fabZ, opgG, yaiW, rutR, clpX, lon, ybfG, ompA, opgH, narW, rnt, lpp, ftnB, wza, wzb, wzc, hcp, yfeK, sbmA, yfeS, yfeX, yfeY, yfgD, bamB, der, bepA, rpoE, rseC, rseA, rseB, bamD, rnlB, dsbC, recJ, prfB, ahpF, bacA, cca, ygiM, ydhI, yraP, hcr, diaA, greA, rpoN, hpf, ptsN, lptB, yhbJ, gspA, fkpA, malQ, yhjJ, yicJ, yieE, plsB
12475934	Excision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts. Proc. Natl. Acad. Sci. U.S.A. Bjorn Rydberg , John Game	2002-12-24	rnhB
11917006	Comparative genomics and evolution of proteins involved in RNA metabolism. Nucleic Acids Res. Vivek Anantharaman , Eugene V Koonin , L Aravind	2002-04-01	-

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