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9448 MAP4K4

9448

MAP4K4

mitogen-activated protein kinase kinase kinase kinase 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitogen-activated protein kinase kinase kinase kinase 4

研究结论

Date Results Publications
2021-01-02 12:50:00 MAP4K4 negatively regulates CD8 T cell-mediated antitumor and antiviral immunity. 32220977
2020-11-21 13:12:00 Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion. 31570734
2020-10-24 14:03:00 STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. 31913126
2020-03-14 12:56:00 These studies highlight a MAP4K4-initiated signaling cascade that induces motor neuron degeneration. 30699345
2019-11-16 11:26:00 TIIA triggered HGK/JNK1-dependent Jun activation and led to increased Jun recruitment to AP-1-binding site in the SESN2 promoter region. 30258193

名称对应

Type IDs
Synonymous FLH21957, HEL-S-31, HGK, MEKKK4, NIK
Gene
UniProtKB-ID: M4K4_HUMAN, V9HWH3_HUMAN, B7Z3V5_HUMAN
UniprotKB: O95819, V9HWH3, B7Z3V5
UniParc: UPI000002A16C, UPI0000141312, UPI0001914B63, UPI0000EE6D9F, UPI000003E780, UPI000002A16B, UPI00000747E2
EMBL: AC007005, AB014587, AY212247, AL137755, AK296396, CH471127, AB013385, AF096300, AC005035, EU794634
Ensembl: ENSG00000071054
KO: hsa:9448
Nucleutide sequences
EMBL-CDS: BAA33714.1, AAD16137.1, EAX01810.1, AAO32626.1, BAA31662.1, CAB70907.2, ACJ13688.1, BAH12341.1
Ensembl_TRS: ENST00000347699, ENST00000350878, ENST00000634702
Protein sequencees
Ensembl_PRO: ENSP00000343658, ENSP00000489579, ENSP00000314363
RefSeq: NP_001371486.1, NP_001371413.1, XP_005264105.1, XP_016860861.1, NP_001371419.1, NP_001371405.1, NP_001371421.1, NP_001371508.1, XP_016860847.1, XP_016860860.1, NP_001371484.1, NP_001371411.1, NP_001371487.1, NP_001371492.1, XP_005264109.1, NP_001371489.1, NP_001371410.1, XP_005264116.1, NP_001371488.1, NP_001371435.1, XP_016860845.1, NP_001371425.1, XP_005264123.1, NP_001371482.1, NP_001371424.1, NP_001371417.1, NP_001371416.1, NP_001371479.1, XP_005264128.1, NP_001371491.1, NP_001371415.1, NP_001371437.1, NP_001371490.1, XP_005264122.1, NP_001371449.1, NP_001371493.1, NP_663720.1, XP_006712928.1, XP_016860858.1, NP_001371480.1, XP_005264114.1, NP_001371426.1, NP_001371436.1, XP_005264120.1, NP_001371438.1, XP_016860849.1, XP_005264119.1, NP_001371501.1, XP_005264117.1, XP_016860846.1, NP_001371406.1, XP_005264125.1, NP_001371485.1, NP_001371420.1, NP_001229489.1, NP_001371472.1, XP_016860855.1, XP_005264126.1, XP_016860857.1, XP_016860852.1, XP_016860862.1, NP_001371496.1, NP_004825.3, NP_001371481.1, NP_001371423.1, NP_663719.2, NP_001371407.1, NP_001371414.1, NP_001229488.1, NP_001371412.1, XP_005264107.1, XP_016860843.1, NP_001371422.1, NP_001371483.1, XP_016860840.1, NP_001371477.1, NP_001371478.1
Others
UniRef100: UniRef100_V9HWH3, UniRef100_O95819, UniRef100_B7Z3V5
UniRef90: UniRef90_O95819, UniRef90_V9HWH3, UniRef90_B7Z3V5
UniRef50: UniRef50_O95819, UniRef50_O95819-3
UniGene: Hs.701013
CCDS: CCDS74546.1, CCDS82487.1, CCDS56130.1

全选

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