| Type | Description |
|---|---|
| Definition | mediator complex subunit 26 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-14 11:08:00 | EAF1 (239-268) and TAF7 (205-235) peptide interactions were both mapped to the same groove formed by H3 and H4 helices of MED26 N-terminal domain. | 28893534 |
| 2016-02-13 12:21:00 | the MED26-NTD functions as a molecular switch in the exchange of TBP-associated factor 7 (TAF7) for LEC to facilitate the transition from initiation to elongation during transcription of a subset of snRNA genes | 25575120 |
| 2011-09-03 10:40:00 | MED26 can function as a molecular switch that interacts first with TFIID in the Pol II initiation complex and then exchanges TFIID for complexes containing ELL/EAF and P-TEFb to facilitate transition of Pol II into the elongation stage of transcription. | 21729782 |
| 2010-01-21 00:00:00 | Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation | 12050112 |
| 2010-01-21 00:00:00 | findings identify MED19/MED26 as a probable composite REST interface in Mediator and further clarify the mechanistic basis by which Mediator facilitates REST-imposed epigenetic restrictions on neuronal gene expression | 19049968 |
| Type | IDs |
|---|---|
| Synonymous | CRSP7, CRSP70 |
| Gene |
UniProtKB-ID:
MED26_HUMAN
UniprotKB:
O95402
UniParc:
UPI000013D3FC,
UPI0000EA2D5D
EMBL:
BC127215,
BC110430,
AF104253
Ensembl:
ENSG00000105085
KO:
hsa:9441
|
| Nucleutide sequences |
EMBL-CDS:
AAD12722.1,
AAI10431.1,
AAI27216.1
Ensembl_TRS:
ENST00000263390,
ENST00000611692
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000484490,
ENSP00000263390
RefSeq:
NP_004822.2
|
| Others |
UniRef100:
UniRef100_O95402
UniRef90:
UniRef90_O95402
UniRef50:
UniRef50_O95402
UniGene:
Hs.715040
CCDS:
CCDS12347.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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