| Type | Description |
|---|---|
| Definition | lysyl oxidase-like 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:41:00 | LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis. | 32296422 |
| 2020-04-18 10:07:00 | for the first time, report the role of Withaferin A in modulating the expression of LOXL2 and Snail1 in addition to vimentin inhibition and regulation of NFkappaB signaling for the treatment of liver fibrosis. | 31336025 |
| 2020-03-28 10:29:00 | Lysyl oxidase-like 2 drives vascular stiffening during aging by promoting matrix remodeling and vascular smooth muscle cell stiffening. | 31002285 |
| 2020-02-15 11:08:00 | Our study demonstrates that systemic LOXL2 adenovirus or LOXL2 genetic overexpression in mice can protect against OA. These findings demonstrate the potential for LOXL2 gene therapy for knee-OA clinical treatment in the future. | 31569601 |
| 2019-06-01 13:14:00 | Study shows that the levels of Loxl2 mRNA and protein are elevated in renal cortex and glomeruli of COL4A3-KO Alport mice, a model for chronic kidney disease. | 29759420 |
| Type | IDs |
|---|---|
| Synonymous | 1110004B06Rik, 4930526G11Rik, 9430067E15Rik |
| Gene |
UniProtKB-ID:
LOXL2_MOUSE
UniprotKB:
P58022
UniParc:
UPI00000E9DB3,
UPI00000EAD17
EMBL:
AK159386,
AF117951,
AK081898,
AK145323,
AK034957,
AK045019
Ensembl:
ENSMUSG00000034205
KO:
mmu:94352
|
| Nucleutide sequences |
EMBL-CDS:
BAC32186.1,
BAE35041.1,
BAC28894.1,
BAE26367.1,
AAF29046.1,
BAC38364.1
Ensembl_TRS:
ENSMUST00000022660,
ENSMUST00000100420
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022660,
ENSMUSP00000097987
RefSeq:
NP_201582.2,
XP_006519810.1,
XP_036014834.1,
XP_006519807.1
|
| Others |
UniRef100:
UniRef100_P58022
UniRef90:
UniRef90_P58022
UniRef50:
UniRef50_P58022
UniGene:
Mm.116714
CCDS:
CCDS27241.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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