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94274 PPP1R14A

94274

PPP1R14A

protein phosphatase 1 regulatory inhibitor subunit 14A

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein phosphatase 1 regulatory inhibitor subunit 14A

研究结论

Date Results Publications
2020-08-29 12:48:00 CPI-17 Overexpression and Its Correlation With the NF2 Mutation Spectrum in Sporadic Vestibular Schwannomas. 31789805
2019-07-20 10:12:00 The down-regulated expression of CPI-17 phosphorylated proteins might be one of the important factors of uterine atony-induced postpartum hemorrhage. 30428734
2018-02-24 11:51:00 CPI-17 drives Ras activity and tumorigenesis in melanomas in a two-fold way; inactivation of the tumor suppressor merlin and activation of the growth promoting ERM family. 27793041
2018-02-17 11:44:00 The authors call the mutual sequestration mechanism through which pCPI-17 and myosin light-chain phosphatase interact inhibition by unfair competition: myosin light-chain phosphatase protects pCPI-17 from other phosphatases, while pCPI-17 blocks other substrates from the active site of myosin light-chain phosphatase. 28387646
2018-02-17 10:48:00 Study finds that CPI-17 (PPP1R14A protein phosphatase 1 regulatory inhibitor subunit 14A, 17 kDa) is not expressed in the healthy peripheral nervous system or in nontumour pathologies of the peripheral nervous system. CPI-17 up-regulation, however, is observed in over 90% of schwannomas, but not in neurofibroma and only rarely in malignant peripheral nerve sheath tumour. 27248983

名称对应

Type IDs
Synonymous CPI-17, CPI17, PPP1INL
Gene
UniProtKB-ID: PP14A_HUMAN
UniprotKB: Q96A00
UniParc: UPI0000072604, UPI00000701DD
EMBL: BC021089, AB056508, AF123763, AB056509, AY050668, AY050670
Ensembl: ENSG00000167641
KO: hsa:94274
Nucleutide sequences
EMBL-CDS: BAB62503.1, AAL25828.1, BAB62502.1, AAL24445.1, AAP97242.1, AAH21089.1
Ensembl_TRS: ENST00000347262, ENST00000301242
Protein sequencees
Ensembl_PRO: ENSP00000301242, ENSP00000301243
RefSeq: NP_150281.1, NP_001230876.1
Others
UniRef100: UniRef100_Q96A00
UniRef90: UniRef90_Q96A00
UniRef50: UniRef50_O18734
UniGene: Hs.631569
CCDS: CCDS58660.1, CCDS12509.1

全选

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