Fkbp6 - FK506 binding protein 6-BMKCloudï½ç¾è¿å®¢äº

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94244 Fkbp6

基因描述

Type	Description
Definition	FK506 binding protein 6

研究结论

Date	Results	Publications
2012-12-22 11:15:00	study identifies a requirement of mouse Fkbp6 for biogenesis of Miwi2 piRNAs	22902560
2012-11-13 09:51:00	Transposon silencing Secondary piRNA biogenesis Cochaperone: interaction with Hsp90	22902560
2010-01-21 00:00:00	fundamental role of Fkbp6 in homologous chromosome synapsis during male meiosis	18408354
2010-01-21 00:00:00	Fkbp6 is a component of the synaptonemal complex essential for sex-specific fertility and for the fidelity of homologous chromosome pairing in meiosis	12764197

名称对应

Type	IDs
Synonymous	1700008G22Rik, 36kDa, AU017274, D5Ertd724e, FKBP-36, FKBP-6
Gene	UniProtKB-ID: FKBP6_MOUSE UniprotKB: Q91XW8 UniParc: UPI0000025ECA, UPI0000025ED6, UPI0000025EBD EMBL: BC139092, AF367711, AK090036, BC139097, AC074359, AF367709, AY029192, AF367710, CH466529 Ensembl: ENSMUSG00000040013 KO: mmu:94244
Nucleutide sequences	EMBL-CDS: AAI39098.1, AAK53413.1, AAI39093.1, AAK53412.1, AAK53411.1, EDL19373.1, EDL19374.1, BAC41058.1, AAK39645.1 Ensembl_TRS: ENSMUST00000044972, ENSMUST00000201534, ENSMUST00000201784, ENSMUST00000201791
Protein sequencees	Ensembl_PRO: ENSMUSP00000144460, ENSMUSP00000043193, ENSMUSP00000144471, ENSMUSP00000144381 RefSeq: NP_001264820.1, XP_030110812.1, XP_030110811.1, XP_011239215.1, NP_291049.1, XP_030110810.1, XP_030110809.1, NP_001264822.1, XP_011239217.1, NP_001264821.1
Others	UniRef100: UniRef100_Q91XW8 UniRef90: UniRef90_Q91XW8 UniRef50: UniRef50_O75344 UniGene: Mm.26037 CCDS: CCDS80425.1, CCDS19738.1, CCDS80426.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
27165042	The enigmatic meiotic dense body and its newly discovered component, SCML1, are dispensable for fertility and gametogenesis in mice. Chromosoma Frantzeskos Papanikos , Katrin Daniel , Angelique Goercharn-Ramlal , Ji-Feng Fei , Thomas Kurth , Lukasz Wojtasz , Ihsan Dereli , Jun Fu , Josef Penninger , Bianca Habermann , Azim Surani , A Francis Stewart , Attila Toth	2017-06-01	-
28378742	Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep Tingting Zhang , Wei Du , Andrew F Wilson , Satoshi H Namekawa , Paul R Andreassen , Amom Ruhikanta Meetei , Qishen Pang	2017-04-05	-
25027326	Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder. Hum. Mol. Genet. Maria Segura-Puimedon , Ignasi SahÃºn , Emilie Velot , Pierre Dubus , Cristina Borralleras , Ana J Rodrigues , MarÃa C Valero , Olga Valverde , Nuno Sousa , Yann Herault , Mara Dierssen , Luis A PÃ©rez-Jurado , Victoria Campuzano	2014-12-15	Gtf2i, Fkbp6
22902560	A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing. Mol. Cell Jordi Xiol , Elisa Cora , Rubina Koglgruber , Shinichiro Chuma , Sailakshmi Subramanian , Mihoko Hosokawa , Michael Reuter , Zhaolin Yang , Philipp Berninger , Andres Palencia , Vladimir Benes , Josef Penninger , Ravi Sachidanandam , Ramesh S Pillai	2012-09-28	Hsp90aa1, Piwil4, Piwil2, Mov10l1, Tdrd1, Fkbp6, Hsp90
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
18408354	Affected homologous chromosome pairing and phosphorylation of testis specific histone, H2AX, in male meiosis under FKBP6 deficiency. J. Reprod. Dev. Junko Noguchi , Manabu Ozawa , Michiko Nakai , TamÃ¡s Somfai , Kazuhiro Kikuchi , Hiroyuki Kaneko , Tetsuo Kunieda	2008-06-01	-
18057311	Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway. Biol. Reprod. Rui Kan , Xianfei Sun , Nadine K Kolas , Elena Avdievich , Burkhard Kneitz , Winfried Edelmann , Paula E Cohen	2008-03-01	Mlh1, Mlh3, Exo1, Fkbp6
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-

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