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94178 Mcoln1

94178

Mcoln1

mucolipin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition mucolipin 1

研究结论

Date Results Publications
2020-11-21 13:16:00 A lysosomal K(+) channel regulates large particle phagocytosis by facilitating lysosome Ca(2+) release. 31974459
2020-10-03 12:58:00 Association of luteal cell degeneration and progesterone deficiency with lysosomal storage disorder mucolipidosis type IV in Mcoln1-/- mouse modeldagger. 31317194
2019-11-09 12:10:00 Findings indicate that TRPML1 mediates diverse roles in adipocyte differentiation and exosomal release. 30711251
2019-10-12 10:58:00 Mice lacking both mucolipins 3 and 1, but not either one alone, experienced hearing loss as early as at 1 month of age. 29453205
2019-09-07 10:13:00 study uncovers a multistep pathway of lysosome formation and identifies TRPML1, a non-selective cation channel protein genetically linked to the lysosomal storage disorder Mucolipidosis type IV, as the crucial regulator of the final step in the lysosome formation pathway 25491304

名称对应

Type IDs
Synonymous 2210015I05Rik, TRPML1, mucolipidin
Gene
UniProtKB-ID: MCLN1_MOUSE
UniprotKB: Q99J21
UniParc: UPI0000020E0C, UPI00003BF757
EMBL: BC005651, AK034471, AK028385, AF302009, AK049606
Ensembl: ENSMUSG00000004567
KO: mmu:94178
Nucleutide sequences
EMBL-CDS: AAH05651.1, BAC25922.1, BAC33838.1, AAL58667.1, BAC28719.1
Ensembl_TRS: ENSMUST00000004683
Protein sequencees
Ensembl_PRO: ENSMUSP00000004683
RefSeq: NP_444407.1
Others
UniRef100: UniRef100_Q99J21
UniRef90: UniRef90_Q99J21
UniRef50: UniRef50_Q99J21
UniGene: Mm.8356
CCDS: CCDS22063.1

全选

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研究热度

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