| Type | Description |
|---|---|
| Definition | histidine-rich glycoprotein |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 12:33:00 | Other HBPs such as alpha 2-HS glycoprotein (AHSG) and histidine-rich glycoprotein (HRG) need further investigation for potential applications in the management of Acute pancreatitis (AP) . Pancreas HBPs are extracellular and so easily accessible and are potential drug targets in AP, whereas plasma HBPs represent potential biomarkers for AP. | 31211768 |
| 2016-09-10 10:27:00 | HRG binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I. | 26051322 |
| 2015-07-04 11:00:00 | Mice deficient in HRG have normal hemostasis, but demonstrate accelerated thrombosis via the contact system. | 25691157 |
| 2015-06-20 10:26:00 | mononuclear phagocytes have specific binding sites for HRG and that these cells are essential for uptake of HRG from blood and distribution of HRG in tissues. Thus, inflammatory cells mediate the effect of HRG on tumor growth and metastatic spread. | 25243896 |
| 2015-06-06 14:57:00 | Results show that HRG is a novel transcriptional target gene of FXR in human hepatoma cells, human upcyteVR primary hepatocytes and 3D human liver microtissues in vitro and in mouse liver in vivo. | 25363753 |
| Type | IDs |
|---|---|
| Synonymous | AI265597, AW413091, D16jh2, D18020, Hprg, Hrgp |
| Gene |
UniProtKB-ID:
HRG_MOUSE,
A0A0R4J039_MOUSE
UniprotKB:
Q9ESB3,
A0A0R4J039
UniParc:
UPI000022F503,
UPI0000022031
EMBL:
AB055898,
BC011168,
AY135662,
AY137504,
CT027991,
AF194028,
AB055897
Ensembl:
ENSMUSG00000022877
KO:
mmu:94175
|
| Nucleutide sequences |
EMBL-CDS:
BAB33094.1,
AAN10183.1,
BAB33095.1,
AAH11168.1,
AAN27996.1,
AAG28416.1
Ensembl_TRS:
ENSMUST00000023590
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023590
RefSeq:
NP_444406.2
|
| Others |
UniRef100:
UniRef100_Q9ESB3
UniRef90:
UniRef90_Q9ESB3
UniRef50:
UniRef50_P04196
UniGene:
Mm.358794
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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