| Type | Description |
|---|---|
| Definition | DEAD-box helicase 23 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 10:40:00 | These data provide new insights into the function of Prp28 in higher eukaryotes, and the requirements for stable tri-small nuclear ribonucleoproteins binding during B complex formation. | 27377154 |
| 2018-04-21 10:10:00 | new basis of DDX23-Linc00630-HDAC1 signal axis for understanding its pathogenicity, which could be further developed as a valuable therapeutic strategy | 28473661 |
| 2017-11-25 15:12:00 | pausing of RNA polymerase II (RNA Pol II) initiates a signaling cascade whereby the serine/arginine protein kinase 2 (SRPK2) phosphorylates the DDX23 helicase, culminating in the suppression of R-loops. | 28076779 |
| 2010-01-21 00:00:00 | SRPK2 knock down results in hypophosphorylation of the arginine-serine (RS) domain-containing human PRP28 protein (PRP28, also known as DDX23), and destabilizes PRP28 association with the tri-snRNP. | 18425142 |
| Type | IDs |
|---|---|
| Synonymous | PRPF28, SNRNP100, U5-100K, U5-100KD, prp28 |
| Gene |
UniProtKB-ID:
DDX23_HUMAN,
A0A024R0Z3_HUMAN,
B3KY11_HUMAN
UniprotKB:
Q9BUQ8,
A0A024R0Z3,
B3KY11
UniParc:
UPI00004DCDE2,
UPI00004A296B,
UPI0000073875
EMBL:
BC002366,
AK312379,
AK128428,
AF026402,
AK294877,
AC117498,
CH471111
Ensembl:
ENSG00000174243
KO:
hsa:9416
|
| Nucleutide sequences |
EMBL-CDS:
EAW58011.1,
BAG57976.1,
AAH02366.1,
AAB87902.1,
BAG35297.1,
EAW58015.1,
BAG54673.1
Gene_ORFName:
hCG_26528
Ensembl_TRS:
ENST00000308025,
ENST00000547135
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000446770,
ENSP00000310723
RefSeq:
NP_004809.2
|
| Others |
UniRef100:
UniRef100_Q9BUQ8,
UniRef100_B3KY11
UniRef90:
UniRef90_Q5RC67,
UniRef90_Q9BUQ8
UniRef50:
UniRef50_Q5RC67,
UniRef50_Q9BUQ8
UniGene:
Hs.130098
CCDS:
CCDS8770.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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