| Type | Description |
|---|---|
| Definition | tight junction protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:11:00 | New tight junction protein 2 variant causing progressive familial intrahepatic cholestasis type 4 in adults: A case report. | 32089630 |
| 2020-05-30 11:55:00 | Supra-molecular assembly and positioning of tight junctions as continuous networks of adhesion strands are dependent on the membrane-associated scaffolding proteins ZO1 and ZO2. | 31675499 |
| 2020-02-29 10:52:00 | It is a potential target of miR-543. | 31428943 |
| 2019-07-13 13:01:00 | Results suggested that a reduction in CLDN18-dependent ZO-2 expression enhances MMP2 expression in lung adenocarcinoma cells, resulting in the promotion of the cell migration. | 30713254 |
| 2019-06-15 11:12:00 | Mutations in the genes responsible for PFIC may be involved in both young and adults with cryptogenic cholestasis in a considerable number of cases, including in heterozygous status. | 29238877 |
| Type | IDs |
|---|---|
| Synonymous | C9DUPq21.11, DFNA51, DUP9q21.11, PFIC4, X104, ZO2 |
| Gene |
UniProtKB-ID:
ZO2_HUMAN,
B7Z2R3_HUMAN,
B7Z954_HUMAN
UniprotKB:
Q9UDY2,
B7Z2R3,
B7Z954
UniParc:
UPI0000141800,
UPI0000141816,
UPI0001C0B37E,
UPI0001915355,
UPI0000367636,
UPI000045775A,
UPI0000169A1A,
UPI0000458967,
UPI0001C0B37F
EMBL:
AK304447,
AF489824,
AF043196,
U84581,
AF177531,
AF083893,
AF177525,
AF177527,
AF083892,
AL162730,
AF177533,
AF177523,
AF177529,
AF177520,
L27476,
AF043195,
AF177522,
AF177530,
AF177528,
AF177518,
AF177532,
AL358113,
AK295016,
AF043197,
AK295034,
AF177519,
AL590238,
BC027592,
AF177521,
AK302483,
AF177526,
AF177524
Ensembl:
ENSG00000119139
KO:
hsa:9414
|
| Nucleutide sequences |
EMBL-CDS:
AAD56219.2,
BAH11954.1,
AAD20387.2,
AAB41794.1,
AAC33121.1,
BAH13722.1,
AAM28524.1,
AAC33122.1,
AAD56218.2,
AAA61300.1,
AAC02527.2,
AAH27592.1,
BAH11949.1,
BAH14190.1
Ensembl_TRS:
ENST00000377245,
ENST00000535702,
ENST00000539225,
ENST00000453658,
ENST00000348208
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366453,
ENSP00000392178,
ENSP00000442090,
ENSP00000438262,
ENSP00000345893
RefSeq:
XP_011517506.1,
NP_001163886.1,
NP_001356804.1,
NP_001356803.1,
NP_004808.2,
NP_963923.1,
XP_011517510.1,
NP_001356800.1,
NP_001356802.1,
XP_011517508.1,
XP_011517511.1,
NP_001163885.1,
NP_001356801.1,
XP_011517509.1,
NP_001356799.1,
NP_001163887.1
|
| Others |
UniRef100:
UniRef100_Q9UDY2,
UniRef100_A0A024R225,
UniRef100_B7Z954
UniRef90:
UniRef90_Q9UDY2-2,
UniRef90_Q9UDY2
UniRef50:
UniRef50_Q9UDY2-2,
UniRef50_Q9UDY2
UniGene:
Hs.50382,
Hs.736223
CCDS:
CCDS55316.1,
CCDS6627.1,
CCDS55315.1,
CCDS6628.1,
CCDS55317.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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