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94121 SYTL4

94121

SYTL4

synaptotagmin like 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition synaptotagmin like 4

研究结论

Date Results Publications
2020-03-21 12:08:00 LMP1 upregulates SDC2 and SYTL4. 31930596
2017-12-16 11:29:00 Determined the solution structure of human synaptotagmin-like protein 4 (Slp4). Through modification of cysteine residues, found Slp4 binding of two zinc atoms is required for correct folding. 28906046
2017-02-18 10:49:00 Granuphilin makes granules immobile and fusion-reluctant beneath the plasma membrane. Those granuphilin-positive, docked granules release a portion of granuphilin upon fusion, and fuse at a frequency and time course similar to those of granuphilin-negative undocked granules. Granuphilin forms a 180-nm cluster at the site of each docked granule, along with granuphilin-interacting Rab27a and Munc18-1 clusters. 27032672
2016-02-13 11:03:00 GLUT5 required an interaction cascade of Rab11, Myo5B, Slp4a, Munc18-2, and Vamp7 with Stx3. 26553929
2015-11-21 11:20:00 Phosphatidylinositol 4,5-bisphosphate binds to the concave surface of granuphilin-C2A domain. The key residues involved in the binding were validated by mutation analysis. 25595293

名称对应

Type IDs
Synonymous SLP4
Gene
UniProtKB-ID: SYTL4_HUMAN, B2R7R4_HUMAN, A0A024RCF8_HUMAN, A8K973_HUMAN, Q71SF7_HUMAN
UniprotKB: Q96C24, B2R7R4, A0A024RCF8, A8K973, Q71SF7
UniParc: UPI00015DA94E, UPI00001BE8A5, UPI000013D38B, UPI00017505DD, UPI00001AE9F2
EMBL: Z73900, AF302493, CH471115, AL832596, BX537410, AL391688, AK094110, BC014913, AK313086, AK292588
Ensembl: ENSG00000102362
KO: hsa:94121
Nucleutide sequences
EMBL-CDS: CAI42005.1, BAC04287.1, CAI46126.1, CAI42004.1, AAH14913.1, CAD97652.1, BAG35911.1, EAX02814.1, EAX02813.1, BAF85277.1, AAQ14492.1
Gene_ORFName: hCG_20193
Ensembl_TRS: ENST00000263033, ENST00000372989, ENST00000276141, ENST00000372981
Protein sequencees
Ensembl_PRO: ENSP00000362072, ENSP00000263033, ENSP00000362080, ENSP00000276141
RefSeq: NP_542775.2, XP_016885455.1, NP_001357090.1, XP_016885458.1, NP_001357089.1, XP_016885459.1, XP_016885457.1, NP_001357097.1, NP_001357094.1, NP_001357096.1, XP_016885456.1, NP_001123368.1, NP_001357091.1, NP_001357098.1, NP_001357095.1, NP_001167539.1, NP_001357093.1, NP_001357092.1
Others
UniRef100: UniRef100_Q96C24, UniRef100_A8K973, UniRef100_B2R7R4, UniRef100_Q71SF7
UniRef90: UniRef90_Q96C24
UniRef50: UniRef50_Q96C24
UniGene: Hs.592224
CCDS: CCDS14472.1

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