| Type | Description |
|---|---|
| Definition | leupaxin |
| Date | Results | Publications |
|---|---|---|
| 2018-08-18 11:11:00 | LPXN may facilitate bladder cancer progression by upregulating the expression of S100P via PI3K/AKT pathway. These results provide a novel insight into the role of LPXN in tumorigenesis and progression of bladder cancer and potential therapeutic target of bladder cancer. | 29975926 |
| 2017-02-04 10:52:00 | this is the first demonstration of a role for the leupaxin in the regulation of hepatocellular carcinoma progression, at least in part, by enhancing beta-catenin transcription activity. | 26361959 |
| 2016-07-30 11:05:00 | The full-length leupaxin binds to the Pyk2-focal adhesion targeting domain. | 26866573 |
| 2016-04-23 10:07:00 | Authors demonstrate that LPXN directly influences cytoskeletal dynamics via interaction with the actin-binding protein CaD and regulates CaD phosphorylation by recruiting ERK to highly dynamic structures within PCa cells. | 26079947 |
| 2016-03-26 11:27:00 | Results show that leupaxin has particular influence on the progression and invasion of breast cancer cells and may therefore represent an interesting candidate protein for diagnosis and therapeutic interventions. | 25955236 |
| Type | IDs |
|---|---|
| Synonymous | LDPL |
| Gene |
UniProtKB-ID:
LPXN_HUMAN,
B7Z5P7_HUMAN
UniprotKB:
O60711,
B7Z5P7
UniParc:
UPI00001FA7B3,
UPI0001914DD6,
UPI000012E82E
EMBL:
AF062075,
CH471076,
AP003557,
AK299264,
AK223165,
BC019035,
AK300955,
AK313306,
AP001350,
CR536531
Ensembl:
ENSG00000110031
KO:
hsa:9404
|
| Nucleutide sequences |
EMBL-CDS:
BAG62583.1,
BAD96885.1,
CAG38768.1,
BAG36111.1,
AAH19035.1,
EAW73808.1,
AAC16014.1,
BAH12983.1
Ensembl_TRS:
ENST00000528954,
ENST00000395074,
ENST00000528489
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378512,
ENSP00000431284,
ENSP00000461855
RefSeq:
XP_011543690.1,
NP_001137467.1,
XP_011543695.1,
NP_001294880.1,
NP_004802.1,
XP_006718813.1,
XP_011543693.1,
XP_011543696.1,
XP_016874068.1,
XP_011543692.1
|
| Others |
UniRef100:
UniRef100_B7Z5P7,
UniRef100_O60711
UniRef90:
UniRef90_A0A5F4WHM2,
UniRef90_O60711
UniRef50:
UniRef50_O60711,
UniRef50_W5PN77
UniGene:
Hs.125474
CCDS:
CCDS53635.1,
CCDS7969.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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