| Type | Description |
|---|---|
| Definition | HtrA serine peptidase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | Expression of HTRA Genes and Its Association with Microsatellite Instability and Survival of Patients with Colorectal Cancer. | 32486357 |
| 2020-07-04 11:45:00 | Our study also reports an intricate ligand-induced allosteric switch, which redefines the existing hypothesis of HtrA3 activation besides opening up avenues for modulating protease activity favorably through suitable effector molecules. | 31899476 |
| 2020-06-20 12:14:00 | HtrA3 isoforms stimulate drug-induced apoptotic death of lung cancer cells via XIAP cleavage. | 31260151 |
| 2020-06-06 12:02:00 | This study reports allosteric modulation of Human HtrA3 (High temperature requirement protease A3) enzyme activity for the first time. A novel non-classical allosteric ligand binding pocket mediates allostery in HtrA3. | 31280864 |
| 2020-05-02 11:43:00 | Low expression of HtrA3 at 15 weeks is associated with, and may be useful for, the early detection of late-onset preeclampsia development and small for gestational age birth. | 31013509 |
| Type | IDs |
|---|---|
| Synonymous | Prsp, Tasp |
| Gene |
UniProtKB-ID:
HTRA3_HUMAN
UniprotKB:
P83110
UniParc:
UPI000019B3C0,
UPI0000001647
EMBL:
AY040094,
AY280666,
BC035717,
AY280665,
BC034390,
AC113611
Ensembl:
ENSG00000170801
KO:
hsa:94031
|
| Nucleutide sequences |
EMBL-CDS:
AAP42283.1,
AAH35717.1,
AAK71475.2,
AAH34390.1,
AAP42282.1
Ensembl_TRS:
ENST00000382512,
ENST00000307358
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000303766,
ENSP00000371952
RefSeq:
NP_001284488.1,
NP_444272.1,
XP_011511898.1
|
| Others |
UniRef100:
UniRef100_P83110
UniRef90:
UniRef90_P83110
UniRef50:
UniRef50_P83110
UniGene:
Hs.479119
CCDS:
CCDS75105.1,
CCDS3400.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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