desK - two-component thermosensor histidine kinase [DesR-DesK]-BMKCloudï½ç¾è¿å®¢äº

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939678 desK

基因描述

Type	Description
Definition	two-component thermosensor histidine kinase [DesR-DesK]

研究结论

Date	Results	Publications
2017-06-24 11:36:00	The thickness of lipid membranes varies with temperature and that such variations can be detected by DesK with great precision.	27528507
2016-07-16 10:33:00	In vivo and biochemical experiments, structural analyses and simulations, demonstrated that stabilization/destabilization of a 2-helix coiled coil is directly involved in regulating DesK's functional state.	26172072
2014-05-10 12:57:00	A lipid-mediated conformational switch modulates the thermosensing activity of DesK.	24522108
2010-01-21 00:00:00	Data from the structural comparison of the different DesK variants indicates that incoming signals can take the form of helix rotations and asymmetric helical bends similar to those reported for other sensing systems.	19805278
2010-01-21 00:00:00	Data show that the membrane-bound histidine kinase DesK phosphorylates the response regulator DesR to activate des transcription.	19595746

名称对应

Type	IDs
Synonymous	BSU19190
Gene	UniProtKB-ID: DESK_BACSU, A0A6M3ZBG3_BACSU UniprotKB: O34757, A0A6M3ZBG3 UniParc: UPI00000604FC EMBL: AL009126, CP052842, CP053102, AF027868 EnsemblGenome: BSU19190 KO: bsu:BSU19190
Nucleutide sequences	EMBL-CDS: AAB84437.1, CAB13811.1, QJP88428.1, QJR46375.1 Gene_ORFName: HIR77_10430, HIR78_10455 EnsemblGenome_TRS: CAB13811
Protein sequencees	EnsemblGenome_PRO: CAB13811 RefSeq: NP_389800.1
Others	UniRef100: UniRef100_O34757 UniRef90: UniRef90_O34757 UniRef50: UniRef50_O34757

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29280348	Bacillus subtilis, the model Gram-positive bacterium: 20Â years of annotation refinement. Microb Biotechnol Rainer Borriss , Antoine Danchin , Colin R Harwood , Claudine MÃ©digue , Eduardo P C Rocha , Agnieszka Sekowska , David Vallenet	2018-01-01	-
27528507	The Single Transmembrane Segment of Minimal Sensor DesK Senses Temperature via a Membrane-Thickness Caliper. J. Bacteriol. Maria E Inda , Rafael G Oliveira , Diego de Mendoza , Larisa E Cybulski	2016-11-01	-
26172072	A coiled coil switch mediates cold sensing by the thermosensory protein DesK. Mol. Microbiol. Emilio Saita , Luciano A Abriata , Yi Ting Tsai , Felipe Trajtenberg , Thomas Lemmin , Alejandro Buschiazzo , Matteo Dal Peraro , Diego de Mendoza , Daniela Albanesi	2015-10-01	-
24522108	A lipid-mediated conformational switch modulates the thermosensing activity of DesK. Proc. Natl. Acad. Sci. U.S.A. MarÃa Eugenia Inda , Michel Vandenbranden , Ariel FernÃ¡ndez , Diego de Mendoza , Jean-Marie Ruysschaert , Larisa EstefanÃa Cybulski	2014-03-04	desK
23429746	An updated metabolic view of the Bacillus subtilis 168 genome. Microbiology (Reading, Engl.) Eugeni Belda , Agnieszka Sekowska , FranÃ§ois Le FÃ¨vre , Anne Morgat , Damien Mornico , Christos Ouzounis , David Vallenet , Claudine MÃ©digue , Antoine Danchin	2013-04-01	-
19595746	Oligomerization of Bacillus subtilis DesR is required for fine tuning regulation of membrane fluidity. Biochim. Biophys. Acta SebastiÃ¡n R Najle , MarÃa E Inda , Diego de Mendoza , Larisa E Cybulski	2009-10-01	desR, desK
19805278	Structural plasticity and catalysis regulation of a thermosensor histidine kinase. Proc Natl Acad Sci U S A Daniela Albanesi , Mariana MartÃn , Felipe Trajtenberg , MarÃa C Mansilla , Ahmed Haouz , Pedro M Alzari , Diego de Mendoza , Alejandro Buschiazzo	2009-09-22	-
19383706	From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Microbiology (Reading) ValÃ©rie Barbe , StÃ©phane Cruveiller , Frank Kunst , Patricia Lenoble , Guillaume Meurice , Agnieszka Sekowska , David Vallenet , Tingzhang Wang , Ivan Moszer , Claudine MÃ©digue , Antoine Danchin	2009-06-01	-
9384377	The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature F Kunst , N Ogasawara , I Moszer , A M Albertini , G Alloni , V Azevedo , M G Bertero , P BessiÃ¨res , A Bolotin , S Borchert , R Borriss , L Boursier , A Brans , M Braun , S C Brignell , S Bron , S Brouillet , C V Bruschi , B Caldwell , V Capuano , N M Carter , S K Choi , J J Cordani , I F Connerton , N J Cummings , R A Daniel , F Denziot , K M Devine , A DÃ¼sterhÃ¶ft , S D Ehrlich , P T Emmerson , K D Entian , J Errington , C Fabret , E Ferrari , D Foulger , C Fritz , M Fujita , Y Fujita , S Fuma , A Galizzi , N Galleron , S Y Ghim , P Glaser , A Goffeau , E J Golightly , G Grandi , G Guiseppi , B J Guy , K Haga , J Haiech , C R Harwood , A HÃ¨naut , H Hilbert , S Holsappel , S Hosono , M F Hullo , M Itaya , L Jones , B Joris , D Karamata , Y Kasahara , M Klaerr-Blanchard , C Klein , Y Kobayashi , P Koetter , G Koningstein , S Krogh , M Kumano , K Kurita , A Lapidus , S Lardinois , J Lauber , V Lazarevic , S M Lee , A Levine , H Liu , S Masuda , C MauÃ«l , C MÃ©digue , N Medina , R P Mellado , M Mizuno , D Moestl , S Nakai , M Noback , D Noone , M O'Reilly , K Ogawa , A Ogiwara , B Oudega , S H Park , V Parro , T M Pohl , D Portelle , S Porwollik , A M Prescott , E Presecan , P Pujic , B Purnelle , G Rapoport , M Rey , S Reynolds , M Rieger , C Rivolta , E Rocha , B Roche , M Rose , Y Sadaie , T Sato , E Scanlan , S Schleich , R Schroeter , F Scoffone , J Sekiguchi , A Sekowska , S J Seror , P Serror , B S Shin , B Soldo , A Sorokin , E Tacconi , T Takagi , H Takahashi , K Takemaru , M Takeuchi , A Tamakoshi , T Tanaka , P Terpstra , A Togoni , V Tosato , S Uchiyama , M Vandebol , F Vannier , A Vassarotti , A Viari , R Wambutt , H Wedler , T Weitzenegger , P Winters , A Wipat , H Yamamoto , K Yamane , K Yasumoto , K Yata , K Yoshida , H F Yoshikawa , E Zumstein , H Yoshikawa , A Danchin	1997-11-20	yozQ, sspN, antE, mrpE, sboX, spsL, kipA, ygaF, sspG, ruvB, sda, sspK, yqzJ, yneP, ygzB, gerT, yojG, dgcW, sspL, ymzD, yezE, sspJ, yrzL, yizA, sspM, ydzU, ykzN, yqzK, yczK, yyzN, yoyI, youA, yezF, skfC, yjzI, rsoA, bsdD, ydzP, yxzL, yczO, yrzR, ykzL, yizB, yyzM, ykzW, ypzJ, yozS, ynzL, ygzC, ybzH, ykzS, yoyG, ytzI, yfzA, yojW, ypzF, epsK, yuzM, yuzL, yqzO, yszA, yczN, yyzH, yrzQ, ydzK, ypzH, yozT, yozV, ykzT, yizD, yoyC, yokU, mstX, yngHB, ylzI, ywzH, yoyF, spoVAEB, ynzK, spoVAEA, yhzD, yjzJ, yvzG, ytzJ, ydzQ, ykzU, fadG, yrzO, ylzH, yczL, yuzJ, ykzP, ypzI, ypzG, yuzI, yozY, yezG, ytrH, yozX

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