| Type | Description |
|---|---|
| Definition | cytosolic iron-sulfur assembly component 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:12:00 | Structural insights into Fe-S protein biogenesis by the CIA targeting complex. | 32632277 |
| 2019-01-05 11:02:00 | CIAO1 role in the iron-sulfur cluster biogenesis.The LYR motif of CIAO1 is required for the interaction with HSC20. | 29309586 |
| 2017-09-09 12:13:00 | Data suggest that CIA2B and MMS19 physically interact with C-terminus of viperin/RSAD2; CIAO1 appears to function as primary viperin-interacting protein; CIA2A binds to N-terminus of viperin in CIAO1-, CIA2B-, and MMS19-independent fashion. (CIA2B = metallochaperone CIA2B/FAM96B; MMS19 = transcription factor MMS19; CIAO1 = cytosolic iron-sulfur assembly component 1; CIA2A = metallochaperone CIA2A/Fam96a) | 28615450 |
| 2017-05-20 10:16:00 | POLE1 is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19. | 27235625 |
| 2015-01-10 11:28:00 | These data suggest that viperin requires CIAO1 for [4Fe-4S] cluster assembly, and acts through an enzymatic, Fe-S cluster- and SAM-dependent mechanism to inhibit viral RNA synthesis. | 24245804 |
| Type | IDs |
|---|---|
| Synonymous | CIA1, WDR39 |
| Gene |
UniProtKB-ID:
CIAO1_HUMAN
UniprotKB:
O76071
UniParc:
UPI0000127987
EMBL:
EF011618,
AC004020,
CR456802,
BC001395,
BC032812,
AK223257,
U63810
Ensembl:
ENSG00000144021
KO:
hsa:9391
|
| Nucleutide sequences |
EMBL-CDS:
AAH01395.1,
AAH32812.1,
CAG33083.1,
ABK41108.1,
AAC24948.1,
BAD96977.1,
AAC23493.1
Ensembl_TRS:
ENST00000488633
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418287
RefSeq:
NP_004795.1,
XP_024309015.1
|
| Others |
UniRef100:
UniRef100_O76071
UniRef90:
UniRef90_O76071
UniRef50:
UniRef50_O76071
UniGene:
Hs.12109
CCDS:
CCDS2019.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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