| Type | Description |
|---|---|
| Definition | ceramide synthase 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-24 11:13:00 | The strong association of LCB levels with neuronal survival both in vivo and in vitro suggests high-level accumulation of LCBs is a possible underlying cause of the CerS1 deficiency-induced neuronal death. | 27162368 |
| 2016-08-27 11:34:00 | CerS1, -2, and -6 are hyperacetylated in the mitochondria of SIRT3-null mice. | 26620563 |
| 2015-12-19 11:40:00 | study is the first comparison of spatial distribution between SM molecular species and CerS isoforms, and revealed their distinct association in the brain. | 26398595 |
| 2014-04-26 10:14:00 | Data indicate that oxidized phospholipids (OxPLs)-induced ceramide synthases (CerS1-Cers6) activity in macrophages is responsible for the accumulation of ceramide. | 23936132 |
| 2013-02-16 12:04:00 | an essential function of CerS1-derived ceramide in the regulation of cerebellar development and neurodevelopmentally regulated behavior. | 23074226 |
| Type | IDs |
|---|---|
| Synonymous | Lass1, Uog-1, to |
| Gene |
UniProtKB-ID:
CERS1_MOUSE,
A2RT05_MOUSE
UniprotKB:
P27545,
A2RT05
UniParc:
UPI0000027E1B
EMBL:
BC132318,
M62301
Ensembl:
ENSMUSG00000087408
KO:
mmu:14559,
mmu:93898
|
| Nucleutide sequences |
EMBL-CDS:
AAA37675.1,
AAI32319.1
Ensembl_TRS:
ENSMUST00000140239
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000120598
RefSeq:
NP_619588.1
|
| Others |
UniRef100:
UniRef100_P27545
UniRef90:
UniRef90_P27545
UniRef50:
UniRef50_P27544
UniGene:
Mm.258280
CCDS:
CCDS52570.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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