| Type | Description |
|---|---|
| Definition | ring finger 111 |
| Date | Results | Publications |
|---|---|---|
| 2016-04-16 11:53:00 | Arkadia, but not the C937A (CA) mutant lacking E3 ubiquitin-ligase activity, induced ubiquitylation and proteasome-dependent degradation of Smad6. | 25762727 |
| 2011-12-17 11:59:00 | Arkadia enhances transforming growth factor-beta signaling responses and supports its tumor-suppressing properties in colorectal cancer. | 21998011 |
| 2011-11-26 11:24:00 | RB1CC1 thus appears to play a unique role as a modulator of TGF-beta signaling by restricting substrate specificity of Arkadia. | 21795712 |
| 2010-09-27 12:41:00 | Trps1 haploinsufficiency enhances TGF-beta1-induced epithelial-to-mesenchymal transition (EMT) and tubulointerstitial fibrosis by modulating the amount of Smad7 through Arkadia/ubiquitin-mediated degradation. | 20507941 |
| 2010-07-19 11:18:00 | findings show that Arkadia regulates the levels of expression of c-Ski protein in cell-type-dependent fashion, and exhibits a tumour suppressor function by inhibiting tumour cell growth | 19959502 |
| Type | IDs |
|---|---|
| Synonymous | ARK, Arkadia |
| Gene |
UniProtKB-ID:
RN111_MOUSE,
A0A1L1SRK3_MOUSE
UniprotKB:
Q99ML9,
A0A1L1SRK3
UniParc:
UPI00001F79FB,
UPI00000239E9,
UPI0003D7471A
EMBL:
BC069835,
AK048110,
AF330197,
BC054842,
AK137148,
AK036351,
AC157086,
AC158995
Ensembl:
ENSMUSG00000032217
KO:
mmu:93836
|
| Nucleutide sequences |
EMBL-CDS:
AAH54842.1,
BAC29394.1,
BAE23252.1,
AAK38272.1,
BAC33245.1,
AAH69835.1
Ensembl_TRS:
ENSMUST00000113595,
ENSMUST00000034739,
ENSMUST00000215848,
ENSMUST00000213647
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000149445,
ENSMUSP00000109225,
ENSMUSP00000034739,
ENSMUSP00000149501
RefSeq:
XP_006511641.1,
XP_036011314.1,
XP_036011315.1,
XP_030100607.1,
XP_011241143.1,
NP_291082.1,
XP_006511640.1,
XP_006511639.1,
XP_006511643.1,
NP_001344423.1,
XP_006511647.1,
XP_030100606.1,
XP_006511646.1,
XP_006511645.1,
XP_017169198.1,
XP_030100610.1,
NP_001361682.1,
XP_030100611.1,
XP_006511644.1,
XP_030100608.1
|
| Others |
UniRef100:
UniRef100_Q99ML9,
UniRef100_A0A1L1SRK3
UniRef90:
UniRef90_Q99ML9
UniRef50:
UniRef50_Q99ML9
UniGene:
Mm.29783
CCDS:
CCDS90614.1,
CCDS23321.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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