| Type | Description |
|---|---|
| Definition | chromosome condensation and segregation SMC ATPase |
| Date | Results | Publications |
|---|---|---|
| 2017-09-30 12:03:00 | Sandwiching of ATP molecules between Smc heads requires them to substantially tilt and translate relative to each other, thereby opening up the Smc arms. This mechanochemical gating reaction regulates chromosome targeting and propose a mechanism for DNA translocation based on the merging of DNA loops upon closure of Smc arms. | 28689660 |
| 2016-12-17 10:51:00 | Targeting of Smc/ScpAB to ParB/parS loading sites is strictly dependent on engagement of Smc head domains and relies on an open organization of the Smc coiled coils. | 26904953 |
| 2014-08-30 10:05:00 | we show that rapid inactivation of SMC or its partner protein ScpB during fast growth leads to a failure to resolve newly replicated origins and a complete block to chromosome segregation. | 24440393 |
| 2013-06-29 11:28:00 | A mutation in SMC that affects ATPase activity and results in exaggerated DNA binding causes a strong segregation defect and affects the localization of the SMC complex, which localizes to many more sites in the cell than under normal conditions | 23475963 |
| 2013-05-04 11:37:00 | An Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complexes. | 23353789 |
| Type | IDs |
|---|---|
| Synonymous | BSU15940 |
| Gene |
UniProtKB-ID:
SMC_BACSU,
A0A6M3ZAX9_BACSU
UniprotKB:
P51834,
A0A6M3ZAX9
UniParc:
UPI000195C5BC
EMBL:
D64116,
D49781,
CP053102,
CP052842,
AL009126
EnsemblGenome:
BSU15940
KO:
bsu:BSU15940
|
| Nucleutide sequences |
EMBL-CDS:
BAA10977.1,
BAA08615.1,
CAB13467.2,
QJP88105.1,
QJR46044.1
Gene_ORFName:
HIR78_08710,
HIR77_08685
EnsemblGenome_TRS:
CAB13467
|
| Protein sequencees |
EnsemblGenome_PRO:
CAB13467
RefSeq:
NP_389476.2
|
| Others |
UniRef100:
UniRef100_P51834
UniRef90:
UniRef90_P51834
UniRef50:
UniRef50_P51834
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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