| Type | Description |
|---|---|
| Definition | ubiquitin-conjugating enzyme E2N |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:54:00 | Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice. | 30867488 |
| 2019-11-02 10:53:00 | Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation | 30254268 |
| 2019-10-12 11:30:00 | UBE2N is a novel regulator of the MEK/FRA1/SOX10 signaling cascade and is indispensable for malignant melanoma growth | 30224375 |
| 2018-12-22 12:17:00 | Together with Riplet, Ube2D3 promotes covalent conjugation of polyubiquitin chains to RIG-I, while Ube2N preferentially facilitates production of unanchored chains. In the presence of these chains, RIG-I induces MAVS aggregation directly on the mitochondria. Data thus reveal two essential mechanisms underlying the activation of RIG-I and MAVS for triggering innate immune signaling in response to viral infection in cells. | 28469175 |
| 2018-04-28 10:48:00 | Study have shown that Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity. | 27796312 |
| Type | IDs |
|---|---|
| Synonymous | 1500026J17Rik, AL022654, BB101821, UBC13 |
| Gene |
UniProtKB-ID:
UBE2N_MOUSE,
A2RTT4_MOUSE
UniprotKB:
P61089,
A2RTT4
UniParc:
UPI0000003EA3
EMBL:
AK161968,
BC034898,
AY039837,
BC067069,
BC138211,
BC132630,
AK005302,
Y09873,
AK005788
Ensembl:
ENSMUSG00000074781
KO:
mmu:93765
|
| Nucleutide sequences |
EMBL-CDS:
BAB23941.1,
BAB24239.1,
CAA71001.1,
BAE36659.1,
AAK74128.1,
AAH34898.3,
AAH67069.1,
AAI38212.1,
AAI32631.1
Ensembl_TRS:
ENSMUST00000099329
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000096932
RefSeq:
XP_006514407.1,
NP_542127.1
|
| Others |
UniRef100:
UniRef100_P61088
UniRef90:
UniRef90_P61088
UniRef50:
UniRef50_P61088
UniGene:
Mm.371667,
Mm.440187,
Mm.486592
CCDS:
CCDS48677.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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