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93739 Gabarapl2

93739

Gabarapl2

gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2

研究结论

Date Results Publications
2017-09-16 12:35:00 Cells that lacked GABARAPs and mice that lacked Gate-16 alone were defective in the IFN-gamma-induced clearance of vacuolar pathogens such as Toxoplasma. Gate-16 specifically associated with the small GTPase ADP-ribosylation factor 1 (Arf1) to mediate uniform distribution of interferon-inducible GTPases. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of IFN-inducible GTPases. 28604719

名称对应

Type IDs
Synonymous 0610012F20Rik, 2900019O08Rik, AI173605, GATE-16, Gef2
Gene
UniProtKB-ID: GBRL2_MOUSE
UniprotKB: P60521
UniParc: UPI0000023921
EMBL: AK002596, BC026798, AK049819, BC081436, AF190644
Ensembl: ENSMUSG00000031950
KO: mmu:93739
Nucleutide sequences
EMBL-CDS: AAH81436.1, BAB22217.1, AAH26798.1, BAC33933.1, AAK16238.1
Ensembl_TRS: ENSMUST00000034428
Protein sequencees
Ensembl_PRO: ENSMUSP00000034428
RefSeq: NP_080969.2
Others
UniRef100: UniRef100_P60520
UniRef90: UniRef90_P60520
UniRef50: UniRef50_P60520
UniGene: Mm.371666
CCDS: CCDS40480.1

全选

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研究热度

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