| Type | Description |
|---|---|
| Definition | AF4/FMR2 family, member 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:59:00 | CircRNA AFF4 promotes osteoblast cells proliferation and inhibits apoptosis via the Mir-7223-5p/PIK3R1 axis. | 31848327 |
| 2015-02-07 11:47:00 | define a specific pairing of two amino acids that creates a salt bridge between MLLT1/3 and AFF proteins that is critically important for MLL-mediated transformation of HPCs | 25282333 |
| 2012-09-22 11:20:00 | AFF4 may therefore help to maintain activation of AMPK downstream signaling under conditions of prolonged stimulation with ghrelin, such as during fasting. | 22528490 |
| 2010-01-21 00:00:00 | Af4 functions as a positive regulator of Pol II transcription elongation factor b (P-TEFb) kinase and, in complex with MLL fusion partners Af9, Enl and Af10, as a mediator of histone H3-K79 methylation by recruiting Dot1 to elongating Pol II | 17135274 |
| 2010-01-21 00:00:00 | AF5q31 (Aff4) is a transcriptional regulator in testicular somatic cells and is essential for male germ cell differentiation and survival. | 16024815 |
| Type | IDs |
|---|---|
| Synonymous | AF5Q31, Alf4, Laf4l, MCEF |
| Gene |
UniProtKB-ID:
AFF4_MOUSE
UniprotKB:
Q9ESC8
UniParc:
UPI0000021598
EMBL:
AK054401,
AF190449,
BC138999,
AK053034,
AK033163
Ensembl:
ENSMUSG00000049470
KO:
mmu:93736
|
| Nucleutide sequences |
EMBL-CDS:
AAI39000.1,
BAC35244.1,
BAC28178.1,
BAC35763.1,
AAG17126.1
Ensembl_TRS:
ENSMUST00000060945
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000051479
RefSeq:
NP_001350260.1,
XP_011247633.1,
NP_291043.1,
XP_030102303.1
|
| Others |
UniRef100:
UniRef100_Q9ESC8
UniRef90:
UniRef90_Q9UHB7
UniRef50:
UniRef50_Q9UHB7
UniGene:
Mm.395281
CCDS:
CCDS24676.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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