| Type | Description |
|---|---|
| Definition | phospholipase A2 activating protein |
| Date | Results | Publications |
|---|---|---|
| 2017-07-29 11:48:00 | In both human and mouse, hypomorphic mutations in the ubiquitin adaptor protein PLAA cause an infantile-lethal neurodysfunction syndrome with seizures. | 28413018 |
| 2017-07-15 10:58:00 | Upon damage, p97 translocates to lysosomes and there cooperates with a distinct set of cofactors including UBXD1, PLAA, and the deubiquitinating enzyme YOD1, which we term ELDR components for Endo-Lysosomal Damage Response. | 27753622 |
| 2017-05-13 21:49:00 | This study presented that Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy. | 28007986 |
| 2015-04-25 11:33:00 | This review provides evidence that 1,25-dihydroxy vitamin D3 stimulates PLA2 via PLAA and CaMKII, a process initiated by Pdia3/PLAA interaction, which further triggers CaMKII-dependent PLA2 activation. [review] | 25448737 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 20574843 |
| Type | IDs |
|---|---|
| Synonymous | DOA1, NDMSBA, PLA2P, PLAP |
| Gene |
UniProtKB-ID:
PLAP_HUMAN
UniprotKB:
Q9Y263
UniParc:
UPI00000372D6
EMBL:
AK223544,
AJ238243,
AK001642,
AK002143,
BC032551,
AL356133,
AF083395,
AL133608,
AF145020
Ensembl:
ENSG00000137055
KO:
hsa:9373
|
| Nucleutide sequences |
EMBL-CDS:
BAA92105.1,
CAB63739.1,
BAA91803.1,
AAD42075.1,
AAD03030.1,
AAH32551.1,
CAB42881.1,
BAD97264.1
Ensembl_TRS:
ENST00000397292
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380460
RefSeq:
NP_001026859.1,
XP_011516374.1,
NP_001308475.1,
XP_016870808.1
|
| Others |
UniRef100:
UniRef100_Q9Y263
UniRef90:
UniRef90_Q9Y263
UniRef50:
UniRef50_Q9Y263
UniGene:
Hs.27182
CCDS:
CCDS35000.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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