| Type | Description |
|---|---|
| Definition | glycoprotein (transmembrane) nmb |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance. | 32694855 |
| 2019-09-14 11:42:00 | this study shows that DC-HIL promotes metastasis by excluding T-Lymphocytes from the pre-metastatic niches | 29857071 |
| 2019-08-31 11:07:00 | The results suggest that Stc1 may be a downstream candidate of Gpnmb, and that both genes interact with other genes in a network to develop glaucoma through mechanisms such as apoptosis and oxidative stress. | 31057322 |
| 2019-07-20 12:37:00 | Under the endoplasmic-reticulum stress conditions, GPNMB relocated to the nucleus and specifically up-regulated expression of BiP at the mRNA level by promoting the BiP pre-mRNA splicing, not through the pathways initiated by the three major transducers of the unfolded protein response: IRE1, PERK, and ATF6. | 28939899 |
| 2019-03-30 10:15:00 | Study using an in vivo model of cutaneous wound healing in mice provide evidence that Gpnmb is functionally important in promoting the recruitment of mesenchymal stem cells to the site of skin injury, which in turn modulates inflammatory responses by directing the M2 polarization of macrophages in acute wound healing. | 28899684 |
| Type | IDs |
|---|---|
| Synonymous | DC-HIL, Dchil, ipd |
| Gene |
UniProtKB-ID:
GPNMB_MOUSE
UniprotKB:
Q99P91
UniParc:
UPI00000232F5
EMBL:
AK076347,
AK171441,
BC026375,
AK170506,
AJ251685,
AK171517,
AK171474,
AK150739,
AK044764,
AF322054,
AK171465,
AK154617
Ensembl:
ENSMUSG00000029816
KO:
mmu:93695
|
| Nucleutide sequences |
EMBL-CDS:
BAE42454.1,
BAC32074.1,
AAH26375.1,
BAE29813.1,
BAE41844.1,
CAB65272.1,
BAE32716.1,
AAK14240.1,
BAE42501.1,
BAE42479.1,
BAE42471.1,
BAC36306.1
Ensembl_TRS:
ENSMUST00000031840
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031840
RefSeq:
NP_444340.3,
XP_036008305.1
|
| Others |
UniRef100:
UniRef100_Q99P91
UniRef90:
UniRef90_Q99P91
UniRef50:
UniRef50_Q14956
UniGene:
Mm.302602
CCDS:
CCDS20122.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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