| Type | Description |
|---|---|
| Definition | casein kinase 1, alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:12:00 | MDMX inhibits casein kinase 1alpha activity and stimulates Wnt signaling. | 32511789 |
| 2020-04-25 12:24:00 | Using a newly described small-molecule, we show that CK1a activators could address a significant unmet clinical need for patients with SMO inhibitor-resistant medulloblastoma, including those harboring mutations in TRP53 | 30487124 |
| 2018-06-09 11:11:00 | Pro-opiomelanocortin (POMC), a precursor of alpha-melanocyte-stimulating hormone (alpha-MSH), was not activated in the CK1alpha ablation-induced hyperpigmentation, which is in contrast to the mechanism of p53-dependent UV tanning. | 28878021 |
| 2017-01-14 11:57:00 | Interactome analyses revealed that the Jade-1S mutant unable to be phosphorylated by CK1alpha has an increased binding affinity to proteins involved in chromatin remodelling, histone deacetylation, transcriptional repression, and ribosome biogenesis. | 26919559 |
| 2016-04-16 10:07:00 | loss of one or two copies in the adipose lineage results in hyperglycaemia | 25994086 |
| Type | IDs |
|---|---|
| Synonymous | 2610208K14Rik, 4632404G05Rik, 5430427P18Rik, CK1a, Csnk1a |
| Gene |
UniProtKB-ID:
Q6PJ87_MOUSE
UniprotKB:
Q6PJ87
UniParc:
UPI0000000151
EMBL:
AK166318,
BC019740,
AK147165,
BC025439
|
| Nucleutide sequences |
EMBL-CDS:
BAE27730.1,
BAE38701.1,
AAH25439.1,
AAH19740.1
|
| Protein sequencees |
RefSeq:
NP_666199.1,
XP_030106506.1,
XP_011245350.1,
XP_006526449.1,
XP_030106505.1,
NP_001344428.1,
NP_001344427.1,
NP_001344429.1,
XP_006526446.1
|
| Others |
UniRef100:
UniRef100_P67827
UniRef90:
UniRef90_P67827
UniRef50:
UniRef50_P67827
UniGene:
Mm.26908
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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