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93679 Trim8

93679

Trim8

tripartite motif-containing 8

protein-coding

Mus musculus

基因描述

Type Description
Definition tripartite motif-containing 8

研究结论

Date Results Publications
2020-10-10 13:02:00 TRIM8 interacts with KIF11 and KIFC1 and controls bipolar spindle formation and chromosomal stability. 31904480
2019-09-14 12:33:00 TRIM8 knockdown effectively protected lipopolysaccharide-induced acute liver failure against inflammation and oxidative stress largely dependent on the promotion of AMPKalpha pathway. 30527811
2017-09-30 13:59:00 these studies reveal an additional regulatory function of TRIM8 in innate immune responses: TRIM8 catalyzes polyubiquitination of TRIF, resulting in disruption of TRIF-TBK1 interaction 28747347
2017-08-12 10:23:00 TRIM8 plays a deleterious role in pressure overload-induced cardiac hypertrophy by accelerating the activation of TAK1-dependent signaling pathways. 27956576
2017-05-27 10:49:00 potent regulator that exacerbates steatohepatitis and metabolic disorders dependent on its binding and ubiquitinating capacity on transforming growth factor-beta-activated kinase 1 27981609

名称对应

Type IDs
Synonymous AA408830, BB006755, GERP, Rnf27
Gene
UniProtKB-ID: TRIM8_MOUSE
UniprotKB: Q99PJ2
UniParc: UPI00005ACEEB
EMBL: BC152343, AF281047, BC152344, AK079847, AF220035, AK052763, BC037065, AK155303
Ensembl: ENSMUSG00000025034
KO: mmu:93679
Nucleutide sequences
EMBL-CDS: BAC35138.1, AAG53088.1, AAI52345.1, BAC37764.1, AAG53489.1, BAE33177.1, AAH37065.1, AAI52344.1
Ensembl_TRS: ENSMUST00000026008
Protein sequencees
Ensembl_PRO: ENSMUSP00000026008
RefSeq: NP_444330.2, XP_006527551.1
Others
UniRef100: UniRef100_Q99PJ2
UniRef90: UniRef90_Q9BZR9
UniRef50: UniRef50_Q9BZR9
UniGene: Mm.392177, Mm.481672
CCDS: CCDS38009.1

全选

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研究热度

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