mecA - adaptor protein controlling oligomerization of the AAA+ protein ClpC-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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936406 mecA

基因描述

Type	Description
Definition	adaptor protein controlling oligomerization of the AAA+ protein ClpC

研究结论

Date	Results	Publications
2019-02-02 11:45:00	MecA inhibits the transcription of several Spo0A-P activated genes, but fails to de-repress several Spo0A-P repressed promoters.	29446505
2011-11-26 11:26:00	MecA downregulates eps expression and spore formation by directly interacting with Spo0A. MecA does not target Spo0A for degradation. It inhibits the transcriptional activity of Spo0A~P by direct binding.	21435029
2010-01-21 00:00:00	ClpCP protease undergoes dynamic cycles of assembly and disassembly, which are triggered by association with MecA and the degradation of MecA, respectively	19767395
2010-01-21 00:00:00	analysis of the crystal structure of the MecA degradation tag	19801546

名称对应

Type	IDs
Synonymous	BSU11520
Gene	UniProtKB-ID: MECA1_BACSU, A0A6M4JF94_BACSU UniprotKB: P37958, A0A6M4JF94 UniParc: UPI0000060212 EMBL: CP053102, AL009126, CP052842, L06059 EnsemblGenome: BSU11520 KO: bsu:BSU11520
Nucleutide sequences	EMBL-CDS: AAC36956.1, CAB13009.1, QJP87661.1, QJR45590.1 Gene_ORFName: HIR77_06335, HIR78_06355 EnsemblGenome_TRS: CAB13009
Protein sequencees	EnsemblGenome_PRO: CAB13009 RefSeq: NP_389034.1
Others	UniRef100: UniRef100_P37958 UniRef90: UniRef90_P37958 UniRef50: UniRef50_P37958

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29446505	ClpC and MecA, components of a proteolytic machine, prevent Spo0A-P-dependent transcription without degradation. Mol. Microbiol. Andrew W Tanner , Valerie J Carabetta , David Dubnau	2018-04-01	-
29280348	Bacillus subtilis, the model Gram-positive bacterium: 20Â years of annotation refinement. Microb Biotechnol Rainer Borriss , Antoine Danchin , Colin R Harwood , Claudine MÃ©digue , Eduardo P C Rocha , Agnieszka Sekowska , David Vallenet	2018-01-01	-
23429746	An updated metabolic view of the Bacillus subtilis 168 genome. Microbiology (Reading, Engl.) Eugeni Belda , Agnieszka Sekowska , FranÃ§ois Le FÃ¨vre , Anne Morgat , Damien Mornico , Christos Ouzounis , David Vallenet , Claudine MÃ©digue , Antoine Danchin	2013-04-01	-
21435029	MecA dampens transitions to spore, biofilm exopolysaccharide and competence expression by two different mechanisms. Mol. Microbiol. Peter Prepiak , Melissa Defrancesco , Sophia Spadavecchia , Nicolas Mirouze , Mark Albano , Marjan Persuh , Masaya Fujita , D Dubnau	2011-05-01	mecA
19801546	Crystal structure of the MecA degradation tag. J Biol Chem Feng Wang , Ziqing Mei , Yutao Qi , Chuangye Yan , Siheng Xiang , Zhiyuan Zhou , Qi Hu , Jiawei Wang , Yigong Shi	2009-12-04	-
19767395	Molecular determinants of MecA as a degradation tag for the ClpCP protease. J Biol Chem Ziqing Mei , Feng Wang , Yutao Qi , Zhiyuan Zhou , Qi Hu , Han Li , Jiawei Wu , Yigong Shi	2009-12-04	-
19383706	From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Microbiology (Reading) ValÃ©rie Barbe , StÃ©phane Cruveiller , Frank Kunst , Patricia Lenoble , Guillaume Meurice , Agnieszka Sekowska , David Vallenet , Tingzhang Wang , Ivan Moszer , Claudine MÃ©digue , Antoine Danchin	2009-06-01	-
9384377	The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature F Kunst , N Ogasawara , I Moszer , A M Albertini , G Alloni , V Azevedo , M G Bertero , P BessiÃ¨res , A Bolotin , S Borchert , R Borriss , L Boursier , A Brans , M Braun , S C Brignell , S Bron , S Brouillet , C V Bruschi , B Caldwell , V Capuano , N M Carter , S K Choi , J J Cordani , I F Connerton , N J Cummings , R A Daniel , F Denziot , K M Devine , A DÃ¼sterhÃ¶ft , S D Ehrlich , P T Emmerson , K D Entian , J Errington , C Fabret , E Ferrari , D Foulger , C Fritz , M Fujita , Y Fujita , S Fuma , A Galizzi , N Galleron , S Y Ghim , P Glaser , A Goffeau , E J Golightly , G Grandi , G Guiseppi , B J Guy , K Haga , J Haiech , C R Harwood , A HÃ¨naut , H Hilbert , S Holsappel , S Hosono , M F Hullo , M Itaya , L Jones , B Joris , D Karamata , Y Kasahara , M Klaerr-Blanchard , C Klein , Y Kobayashi , P Koetter , G Koningstein , S Krogh , M Kumano , K Kurita , A Lapidus , S Lardinois , J Lauber , V Lazarevic , S M Lee , A Levine , H Liu , S Masuda , C MauÃ«l , C MÃ©digue , N Medina , R P Mellado , M Mizuno , D Moestl , S Nakai , M Noback , D Noone , M O'Reilly , K Ogawa , A Ogiwara , B Oudega , S H Park , V Parro , T M Pohl , D Portelle , S Porwollik , A M Prescott , E Presecan , P Pujic , B Purnelle , G Rapoport , M Rey , S Reynolds , M Rieger , C Rivolta , E Rocha , B Roche , M Rose , Y Sadaie , T Sato , E Scanlan , S Schleich , R Schroeter , F Scoffone , J Sekiguchi , A Sekowska , S J Seror , P Serror , B S Shin , B Soldo , A Sorokin , E Tacconi , T Takagi , H Takahashi , K Takemaru , M Takeuchi , A Tamakoshi , T Tanaka , P Terpstra , A Togoni , V Tosato , S Uchiyama , M Vandebol , F Vannier , A Vassarotti , A Viari , R Wambutt , H Wedler , T Weitzenegger , P Winters , A Wipat , H Yamamoto , K Yamane , K Yasumoto , K Yata , K Yoshida , H F Yoshikawa , E Zumstein , H Yoshikawa , A Danchin	1997-11-20	yozQ, sspN, antE, mrpE, sboX, spsL, kipA, ygaF, sspG, ruvB, sda, sspK, yqzJ, yneP, ygzB, gerT, yojG, dgcW, sspL, ymzD, yezE, sspJ, yrzL, yizA, sspM, ydzU, ykzN, yqzK, yczK, yyzN, yoyI, youA, yezF, skfC, yjzI, rsoA, bsdD, ydzP, yxzL, yczO, yrzR, ykzL, yizB, yyzM, ykzW, ypzJ, yozS, ynzL, ygzC, ybzH, ykzS, yoyG, ytzI, yfzA, yojW, ypzF, epsK, yuzM, yuzL, yqzO, yszA, yczN, yyzH, yrzQ, ydzK, ypzH, yozT, yozV, ykzT, yizD, yoyC, yokU, mstX, yngHB, ylzI, ywzH, yoyF, spoVAEB, ynzK, spoVAEA, yhzD, yjzJ, yvzG, ytzJ, ydzQ, ykzU, fadG, yrzO, ylzH, yczL, yuzJ, ykzP, ypzI, ypzG, yuzI, yozY, yezG, ytrH, yozX

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