| Type | Description |
|---|---|
| Definition | synaptonemal complex central element protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:21:00 | Consanguineous Chinese Familial Study Reveals that a Gross Deletion that Includes the SYCE1 Gene Region Is Associated with Premature Ovarian Insufficiency. | 31925770 |
| 2020-12-05 13:04:00 | The second mutation of SYCE1 gene associated with autosomal recessive nonobstructive azoospermia. | 31916078 |
| 2020-05-23 10:47:00 | Structural core of SYCE1 is formed by amino acids 25-179, within N-terminal half of protein, which mediates SYCE1 dimerization. This alpha-helical core adopts curved coiled-coil structure of 20-nm length in which two chains are arranged in anti-parallel configuration. Structure is retained within full-length SYCE1, in which long C-termini adopt extended conformations to achieve an elongated molecule of over 50nm in length | 30607510 |
| 2016-05-07 11:06:00 | A mutation in SYCE1 is associated with non-obstructive azoospermia. | 25899990 |
| 2015-01-24 11:52:00 | Given the known function of the SYCE1 gene, we suggest that the nonsense mutation identified accounts for the primary ovarian insufficiency phenotype. | 25062452 |
| Type | IDs |
|---|---|
| Synonymous | C10orf94, CT76, POF12, SPGF15 |
| Gene |
UniProtKB-ID:
SYCE1_HUMAN,
A0A0B4J1R9_HUMAN
UniprotKB:
Q8N0S2,
A0A0B4J1R9
UniParc:
UPI000013F901,
UPI000006F08E,
UPI000003AEA3,
UPI00000710F3
EMBL:
AK314978,
AY027808,
AY027807,
AY028079,
BC034821,
AL161645,
CH471211
Ensembl:
ENSG00000171772
KO:
hsa:93426
|
| Nucleutide sequences |
EMBL-CDS:
AAH34821.1,
AAK14797.1,
AAK21976.1,
BAG37477.1,
AAK14796.1,
EAW61359.1
Ensembl_TRS:
ENST00000343131,
ENST00000368517,
ENST00000303903
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357503,
ENSP00000341282,
ENSP00000303978
RefSeq:
NP_001137236.1,
NP_001137235.1,
NP_570140.1
|
| Others |
UniRef100:
UniRef100_A0A0B4J1R9,
UniRef100_Q8N0S2
UniRef90:
UniRef90_Q8N0S2,
UniRef90_Q4R7J8
UniRef50:
UniRef50_Q8N0S2
UniGene:
Hs.553795
CCDS:
CCDS7687.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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