| Type | Description |
|---|---|
| Definition | CCR4-NOT transcription complex subunit 8 |
| Date | Results | Publications |
|---|---|---|
| 2015-09-26 21:42:00 | These results indicate that Caf1 and Ccr4 cooperate in mRNA deadenylation and suggest that the enzyme activities of Caf1 and Ccr4 are regulated via allosteric interactions within the nuclease module. | 25944446 |
| 2015-05-16 11:24:00 | CNOT7/hCAF1 is involved in ICAM-1 and IL-8 regulation by TTP in HPMEC. | 25038453 |
| 2014-05-17 10:16:00 | The loss of CAF-1 p48 subunit causes a strong defect in packaging DNA into nucleosomes. | 24036545 |
| 2013-11-30 10:47:00 | show that SMG7 binds directly to POP2, a catalytic subunit of the CCR4-NOT deadenylase complex, and elicits deadenylation-dependent decapping and 5'-to-3' decay of NMD targets | 24115769 |
| 2013-06-15 11:00:00 | The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex. | 23236473 |
| Type | IDs |
|---|---|
| Synonymous | CAF1, CALIF, Caf1b, POP2, hCAF1 |
| Gene |
UniProtKB-ID:
CNOT8_HUMAN,
B7Z9U0_HUMAN
UniprotKB:
Q9UFF9,
B7Z9U0
UniParc:
UPI000191535D,
UPI0000000E08,
UPI00005C191C,
UPI00004235E7
EMBL:
BC017366,
AF180476,
AK316269,
AK315864,
AK303775,
BT006857,
AK025358,
AK316221,
AK316055,
AF053318,
AF087844,
AC112169,
AK314317,
CH471062,
AK297381,
AL122045
Ensembl:
ENSG00000155508
KO:
hsa:9337
|
| Nucleutide sequences |
EMBL-CDS:
BAG36965.1,
AAH17366.1,
BAH14640.1,
EAW61625.1,
BAF98755.1,
BAB15119.1,
EAW61627.1,
EAW61628.1,
BAH12567.1,
EAW61626.1,
CAB59181.1,
AAD02685.1,
AAF29830.1,
AAP97157.1,
AAP35503.1,
BAH14047.1,
BAH14592.1,
BAH14426.1
Ensembl_TRS:
ENST00000517876,
ENST00000520671,
ENST00000285896,
ENST00000521583,
ENST00000523698,
ENST00000403027,
ENST00000519404,
ENST00000521450,
ENST00000524105
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000430493,
ENSP00000428565,
ENSP00000428305,
ENSP00000429882,
ENSP00000285896,
ENSP00000384747,
ENSP00000430833,
ENSP00000431034,
ENSP00000429576
RefSeq:
XP_016865542.1,
NP_001288003.1,
XP_016865541.1,
NP_001288002.1,
NP_001288009.1,
NP_001288011.1,
NP_001288012.1,
NP_001288015.1,
XP_011536008.1,
XP_016865543.1,
XP_016865546.1,
XP_016865539.1,
XP_011536010.1,
XP_005268584.1,
XP_016865537.1,
XP_016865547.1,
NP_004770.4,
XP_016865538.1,
NP_001288006.1,
XP_016865544.1,
XP_016865540.1,
XP_016865545.1,
NP_001288004.1
|
| Others |
UniRef100:
UniRef100_Q9UFF9
UniRef90:
UniRef90_Q9UFF9
UniRef50:
UniRef50_Q9UFF9
UniGene:
Hs.26703
CCDS:
CCDS78074.1,
CCDS4329.1,
CCDS75361.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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