| Type | Description |
|---|---|
| Definition | CD22 molecule |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | Glycoengineering of NK Cells with Glycan Ligands of CD22 and Selectins for B-Cell Lymphoma Therapy. | 33314603 |
| 2021-03-20 13:28:00 | Inotuzumab ozogamicin resistance associated with a novel CD22 truncating mutation in a case of B-acute lymphoblastic leukaemia. | 32648276 |
| 2021-02-06 13:55:00 | Humanized CD22 transgenic mouse model for in vivo analysis of anti-CD22-based immunotherapy. | 32592176 |
| 2020-09-19 16:22:00 | N-Linked Glycosylation Regulates CD22 Organization and Function. | 31019513 |
| 2019-10-26 11:14:00 | CD22 plays a key role in affecting B cell responses to antigens and innate immune signals, and CD22-CD22L interactions are essential for maintaining self-tolerance. The ability of CD22 to regulate both B cell receptor and toll-like receptors represents an attractive therapeutic strategy for manipulating B cell responses in autoimmunity. | 30323814 |
| Type | IDs |
|---|---|
| Synonymous | SIGLEC-2, SIGLEC2 |
| Gene |
UniProtKB-ID:
CD22_HUMAN,
Q0EAF5_HUMAN
UniprotKB:
P20273,
Q0EAF5
UniParc:
UPI00005DC76E,
UPI0001639C50,
UPI000002A5E7,
UPI0001639822,
UPI000012733D
EMBL:
AB012999,
AB012998,
BC109306,
X52785,
AB013004,
AB013006,
AB253795,
AB012996,
AB013002,
EF064756,
AC002132,
AB012995,
AK225625,
X59350,
AB012997,
AB013003,
AB253794,
U62631,
AB013000,
AB253793
Ensembl:
ENSG00000012124
KO:
hsa:933
|
| Nucleutide sequences |
EMBL-CDS:
BAA36575.1,
CAA42006.1,
BAA36571.1,
BAA36565.1,
BAA36568.1,
AAB06448.1,
AAI09307.1,
AAB06449.1,
BAA36572.1,
BAA36566.1,
BAA36564.1,
BAA36567.1,
BAA36573.1,
BAA36569.1,
CAA36988.1,
BAF32756.1,
ABK41939.1,
BAF32757.1,
BAF32758.1
Ensembl_TRS:
ENST00000341773,
ENST00000594250,
ENST00000536635,
ENST00000419549,
ENST00000085219,
ENST00000544992
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000442279,
ENSP00000441237,
ENSP00000339349,
ENSP00000085219,
ENSP00000469984,
ENSP00000403822
RefSeq:
NP_001762.2,
NP_001172029.1,
NP_001172030.1,
NP_001265346.1,
NP_001172028.1
|
| Others |
UniRef100:
UniRef100_P20273
UniRef90:
UniRef90_P20273
UniRef50:
UniRef50_P20273
UniGene:
Hs.579691
CCDS:
CCDS12457.1,
CCDS54247.1,
CCDS54248.1,
CCDS62634.1,
CCDS54249.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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