| Type | Description |
|---|---|
| Definition | thyroid hormone receptor interactor 10 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 13:09:00 | CIP4 phosphorylation is associated with cancer cell invasiveness and metastasis. | 31319138 |
| 2019-05-11 12:58:00 | FBP17 and CIP4 prime the membrane of resting cells for fast endophilin-mediated endocytosis by recruiting the 5'-lipid phosphatase SHIP2 and lamellipodin to mediate the local production of phosphatidylinositol-3,4-bisphosphate and endophilin pre-enrichment. | 30061681 |
| 2019-05-11 12:25:00 | In cultured colorectal cancer (CRC) cells, knockdown of AKAP-9 inhibited cell proliferation, invasion, and migration. AKAP-9 deficiency also attenuated CRC tumor growth and metastasis in vivo. Mechanistically, AKAP-9 interacted with cdc42 interacting protein 4 (CIP4) and regulated its expression. | 27039663 |
| 2017-12-16 11:09:00 | Data show that CIP4 is highly expressed in nasopharyngeal carcinoma (NPC) tissues and is associated with poor prognosis. Also, the study provides evidence that CIP4 plays an important role in the promotion of NPC metastasis by mediating invadopodia formation and activating the EGFR pathway. | 28129778 |
| 2016-06-04 12:10:00 | results support a model in which AKAP350 recruits CIP4 to the centrosome, providing a centrosomal scaffold to integrate microtubule and actin dynamics, thus enabling centrosome polarization and ensuring cell migration directionality. | 26208639 |
| Type | IDs |
|---|---|
| Synonymous | CIP4, HSTP, STOT, STP, TRIP-10 |
| Gene |
UniProtKB-ID:
CIP4_HUMAN,
W4VSQ9_HUMAN
UniprotKB:
Q15642,
W4VSQ9
UniParc:
UPI00001279E3,
UPI0000E8259A,
UPI000006DB86,
UPI000006E4F2,
UPI000059D64B,
UPI00000706DA
EMBL:
L40379,
AY081141,
BT020171,
AF380114,
AJ000414,
AC008760,
AF502289,
AB072596,
BT006698,
CH471139,
CR536513,
BT020167,
BC013002,
AK313296,
AK223109
Ensembl:
ENSG00000125733
KO:
hsa:9322
|
| Nucleutide sequences |
EMBL-CDS:
AAV38969.1,
EAW69063.1,
AAM46851.1,
AAH13002.1,
AAV43773.1,
AAC41729.1,
EAW69065.1,
AAK77492.1,
EAW69062.1,
CAG38751.1,
BAD96829.1,
AAL89588.1,
CAA04062.1,
AAP35344.1,
BAG36103.1,
BAB88853.1,
EAW69060.1
Gene_ORFName:
hCG_23056
Ensembl_TRS:
ENST00000313285,
ENST00000313244,
ENST00000596758
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320117,
ENSP00000320493,
ENSP00000469360
RefSeq:
NP_001275891.1,
XP_005259740.1,
NP_001275892.1,
XP_006723003.1,
NP_004231.1
|
| Others |
UniRef100:
UniRef100_Q15642,
UniRef100_W4VSQ9
UniRef90:
UniRef90_Q15642-3,
UniRef90_Q15642
UniRef50:
UniRef50_Q15642
UniGene:
Hs.515094
CCDS:
CCDS74272.1,
CCDS74271.1,
CCDS12172.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员