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9320 TRIP12

9320

TRIP12

thyroid hormone receptor interactor 12

protein-coding

Homo sapiens

基因描述

Type Description
Definition thyroid hormone receptor interactor 12

研究结论

Date Results Publications
2021-04-17 13:18:00 Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12. 33824312
2021-04-17 13:15:00 TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains. 33567268
2021-01-09 13:26:00 Clark-Baraitser syndrome is associated with a nonsense alteration in the autosomal gene TRIP12. 31814248
2020-12-12 13:24:00 The E3 ubiquitin ligase TRIP12 participates in cell cycle progression and chromosome stability. 31964993
2017-09-30 13:47:00 p16 overexpression led to downregulation of TRIP12, which in turn led to increased RNF168 levels, repressed DNA damage repair (DDR), increased 53BP1 foci and enhanced radioresponsiveness. 27425591

名称对应

Type IDs
Synonymous MRD49, TRIP-12, ULF
Gene
UniProtKB-ID: TRIPC_HUMAN
UniprotKB: Q14669
UniParc: UPI000013739D, UPI0000DA6BE7, UPI0000422081, UPI0000DA6BD4
EMBL: BC113891, AC105380, AC009973, AC093384, D28476, L40383, BC114556, EU489742
Ensembl: ENSG00000153827
KO: hsa:9320
Nucleutide sequences
EMBL-CDS: AAC41731.1, BAA05837.2, AAY14755.1, AAY14681.1, AAI13892.1, AAI14557.1, ACC99349.1
Ensembl_TRS: ENST00000283943, ENST00000389044, ENST00000389045
Protein sequencees
Ensembl_PRO: ENSP00000373697, ENSP00000373696, ENSP00000283943
RefSeq: NP_001335254.1, XP_024308991.1, XP_024309001.1, XP_024308992.1, NP_001335244.1, NP_001335258.1, XP_005247018.1, NP_001335255.1, NP_001271144.1, NP_001335250.1, NP_001271143.1, XP_024309002.1, NP_001335257.1, XP_024309009.1, NP_001335263.1, XP_016860772.1, NP_001335253.1, XP_024309004.1, XP_024308994.1, NP_001335251.1, XP_024308999.1, NP_001335247.1, XP_024309011.1, NP_001335261.1, XP_024309000.1, XP_024308996.1, XP_024308993.1, XP_024308995.1, NP_001335264.1, XP_024309005.1, XP_024309008.1, NP_001335246.1, NP_001271145.1, NP_001335259.1, XP_024308998.1, NP_004229.1, NP_001335252.1, XP_024308997.1, XP_024309010.1, NP_001335249.1, XP_024309007.1, XP_016860778.1, NP_001335265.1, XP_016860779.1, NP_001335260.1, XP_024309006.1, NP_001335262.1, NP_001335248.1, NP_001335245.1, NP_001335256.1, XP_024309003.1
Others
UniRef100: UniRef100_Q14669
UniRef90: UniRef90_Q14669
UniRef50: UniRef50_Q14669
UniGene: Hs.591633
CCDS: CCDS33391.1, CCDS63146.1, CCDS63145.1

全选

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研究热度

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