| Type | Description |
|---|---|
| Definition | immunoglobulin superfamily member 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:00:00 | EWI-2 Inhibits at the HIV-1 Virological Presynapse. | 31757023 |
| 2015-12-19 11:03:00 | EWI-2 negatively regulates TGF-beta signaling and its downstream events including cytostasis (in vitro and in vivo), EMT-like changes, cell migration, CD271-dependent invasion, and lung metastasis (in vivo). | 25656846 |
| 2013-12-28 11:23:00 | Authors demonstrated that EWI-2wint promotes CD81 clustering and confinement in CD81-enriched areas. | 23351194 |
| 2012-11-24 11:18:00 | The EWI-2/alpha-actinin complex is involved in regulation of the actin cytoskeleton at T cell immune and virological synapses, providing a link between membrane microdomains and the formation of polarized membrane structures involved in T cell recognition. | 22689882 |
| 2012-04-26 16:09:00 | A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. | 22360420 |
| Type | IDs |
|---|---|
| Synonymous | CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL |
| Gene |
UniProtKB-ID:
IGSF8_HUMAN
UniprotKB:
Q969P0
UniParc:
UPI00006A77E9,
UPI0000073CBA,
UPI0000071A17
EMBL:
AY157579,
AF311906,
AY044845,
AK055843,
AF407274,
BC053881,
BC004108
Ensembl:
ENSG00000162729
KO:
hsa:93185
|
| Nucleutide sequences |
EMBL-CDS:
BAB71027.1,
AAH53881.1,
AAK92220.1,
AAM94901.1,
AAO13163.1,
AAL01052.1,
AAH04108.2
Ensembl_TRS:
ENST00000368086,
ENST00000614243,
ENST00000314485
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316664,
ENSP00000357065,
ENSP00000477565
RefSeq:
XP_016858324.1,
XP_016858325.1,
XP_016858328.1,
XP_024306713.1,
XP_024306715.1,
XP_016858329.1,
NP_001307176.1,
XP_006711694.1,
NP_443100.1,
XP_016858327.1,
XP_016858326.1,
NP_001193594.1
|
| Others |
UniRef100:
UniRef100_Q969P0
UniRef90:
UniRef90_Q969P0
UniRef50:
UniRef50_Q969P0
UniGene:
Hs.332012
CCDS:
CCDS1195.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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