| Type | Description |
|---|---|
| Definition | PR/SET domain 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 10:17:00 | we detected a novel obesity and BMI-associated locus at PKHD1 and novel variants driving associations at previously established signals (e.g. rs205262 at the SNRPC/C6orf106 locus and rs112446794 at the PRDM6-CEP120 locus). | 30677029 |
| 2017-05-13 22:24:00 | Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. | 27181681 |
| 2015-07-25 11:30:00 | Three novel loci were identified in East Asians with cardiac arrhythmias: rs2483280 (PRDM16 locus) and rs335206 (PRDM6 locus) were associated with QRS duration; and rs17026156 (SLC8A1 locus) correlated with PR interval. | 25035420 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | KMT8C, PDA3, PRISM |
| Gene |
UniProtKB-ID:
PRDM6_HUMAN
UniprotKB:
Q9NQX0
UniParc:
UPI00001C1E2E,
UPI00018E1825,
UPI0001610E83
EMBL:
AF272899,
AC106786,
AC008548,
AF272898
Ensembl:
ENSG00000061455
KO:
hsa:93166
|
| Nucleutide sequences |
EMBL-CDS:
AAF78078.1,
AAF78079.1
Ensembl_TRS:
ENST00000407847
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384725
RefSeq:
XP_011542028.1,
NP_001129711.1
|
| Others |
UniRef100:
UniRef100_Q9NQX0
UniRef90:
UniRef90_Q9NQX0
UniRef50:
UniRef50_Q9NQX0
UniGene:
Hs.135118
CCDS:
CCDS47259.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30677029 |
Genetic architecture of human thinness compared to severe obesity. PLoS Genet Fernando Riveros-McKay , Vanisha Mistry , Rebecca Bounds , Audrey Hendricks , Julia M Keogh , Hannah Thomas , Elana Henning , Laura J Corbin , Understanding Society Scientific Group , Stephen O'Rahilly , Eleftheria Zeggini , Eleanor Wheeler , Inês Barroso , I Sadaf Farooqi |
2019-01-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27716515 |
Am. J. Hum. Genet. Na Li , Lakshman Subrahmanyan , Emily Smith , Xiaoqing Yu , Samir Zaidi , Murim Choi , Shrikant Mane , Carol Nelson-Williams , Mohaddeseh Behjati , Mohammad Kazemi , Mohammad Hashemi , Mohsen Fathzadeh , Anand Narayanan , Likun Tian , Farhad Montazeri , Mitra Mani , Michael L Begleiter , Brian G Coon , Henry T Lynch , Eric N Olson , Hongyu Zhao , Jürgen Ruland , Richard P Lifton , Arya Mani |
2016-10-06 | - |
| 27181681 |
Am. J. Hum. Genet. Na Li , Lakshman Subrahmanyan , Emily Smith , Xiaoqing Yu , Samir Zaidi , Murim Choi , Shrikant Mane , Carol Nelson-Williams , Mohaddeseh Behjati , Mohammad Kazemi , Mohammad Hashemi , Mohsen Fathzadeh , Anand Narayanan , Likun Tian , Farhad Montazeri , Mitra Mani , Michael L Begleiter , Brian G Coon , Henry T Lynch , Eric N Olson , Hongyu Zhao , Jürgen Ruland , Richard P Lifton , Arya Mani |
2016-06-02 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25609649 |
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Mol. Syst. Biol. Xu Li , Wenqi Wang , Jiadong Wang , Anna Malovannaya , Yuanxin Xi , Wei Li , Rudy Guerra , David H Hawke , Jun Qin , Junjie Chen |
2015-01-01 |
ABI1,
ZBTB33,
TCF24,
RPL29P11,
FOXO6,
HDAC6,
HDAC5,
MEF2B,
CHAF1A,
PARP2,
HMGXB4,
SMC4,
FARSB,
HUWE1,
RAD50,
SUGP2,
ABI2,
WASF2,
ALYREF,
TSHZ1,
DDX39A,
TRIB1,
GPHN,
AKAP8,
STAG1,
SF3A1,
TNIP1,
ADAR,
HMG20B,
IRF9,
MYL12B,
MYL9,
CFDP1,
MCRS1,
TOMM40,
CDX2,
COG5,
HOXB13,
LRRC41,
NCOA2,
CEBPB,
KAT5,
SLU7,
DRAP1,
SMC2,
CENPB,
PRPF8,
MXD4,
P3H4,
TRIM3,
ARID3B,
STAG2,
NCKAP1,
IQGAP2,
ZNF268,
UTP14A,
MRPS30,
BRD8,
TCERG1,
MORF4,
POP1,
SF3A3,
SF3B2,
KIF2C,
ATF7,
TMED1,
RCC1,
DDX52,
CHD4,
FOXN3,
PSIP1,
WDHD1,
CHI3L2,
BAZ1A,
NISCH,
CHEK2,
MRPL3,
PNKP,
SGF29,
NACC1,
ACOT7,
LACTB,
DNTTIP1,
FOXP4,
IKBIP,
JDP2,
ANKRD26P1,
HEXIM2,
C17orf49,
NDUFA11,
PUSL1,
COPA,
MAP3K8,
LIN54,
C5orf24,
COX7A2,
CPOX,
CPS1,
NACC2
|
| 25035420 |
Hum. Mol. Genet. Kyung-Won Hong , Ji Eun Lim , Jong Wook Kim , Yasuharu Tabara , Hirotsugu Ueshima , Tetsuro Miki , Fumihiko Matsuda , Yoon Shin Cho , Yeonjung Kim , Bermseok Oh |
2014-12-15 |
LOC101929667,
CDKN1A,
SETBP1,
SCN5A,
SCN10A,
PRDM16,
GAREM1,
SLC8A1,
TBX5,
TBX3,
SAP30L,
CAV1,
CAV2,
PRDM6,
HAND1,
EXOG
|
| 25342443 |
Nat Commun Sara Lindström , Deborah J Thompson , Andrew D Paterson , Jingmei Li , Gretchen L Gierach , Christopher Scott , Jennifer Stone , Julie A Douglas , Isabel dos-Santos-Silva , Pablo Fernandez-Navarro , Jajini Verghase , Paula Smith , Judith Brown , Robert Luben , Nicholas J Wareham , Ruth J F Loos , John A Heit , V Shane Pankratz , Aaron Norman , Ellen L Goode , Julie M Cunningham , Mariza deAndrade , Robert A Vierkant , Kamila Czene , Peter A Fasching , Laura Baglietto , Melissa C Southey , Graham G Giles , Kaanan P Shah , Heang-Ping Chan , Mark A Helvie , Andrew H Beck , Nicholas W Knoblauch , Aditi Hazra , David J Hunter , Peter Kraft , Marina Pollan , Jonine D Figueroa , Fergus J Couch , John L Hopper , Per Hall , Douglas F Easton , Norman F Boyd , Celine M Vachon , Rulla M Tamimi |
2014-10-24 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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