| Type | Description |
|---|---|
| Definition | membrane spanning 4-domains A1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:23:00 | Pharmacokinetics and safety of IBI301 versus rituximab in patients with CD20(+) B-cell lymphoma: a multicenter, randomized, double-blind, parallel-controlled study. | 32669656 |
| 2020-10-24 14:04:00 | STIM1 knock-down decreases the affinity of obinutuzumab for CD20 by altering CD20 localization to Triton-soluble membrane. | 32056202 |
| 2020-06-20 10:32:00 | CD20 deletion has no effect upon B-cell receptor signaling or calcium flux. Also B-cell survival and proliferation is unaffected in the absence of CD20. | 32210425 |
| 2020-04-11 11:13:00 | this study obtained a structure of CD20 in complex with rituximab (RTX), revealing CD20 as a compact double-barrel dimer bound by two RTX antigen-binding fragments (Fabs), each of which engages a composite epitope and an extensive homotypic Fab:Fab interface. | 32079680 |
| 2020-02-22 10:34:00 | Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies. | 31669559 |
| Type | IDs |
|---|---|
| Synonymous | B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7 |
| Gene |
UniProtKB-ID:
CD20_HUMAN,
A0A024R507_HUMAN
UniprotKB:
P11836,
A0A024R507
UniParc:
UPI000012733B,
UPI00017A7AD3
EMBL:
L23415,
AK300025,
CH471076,
M27395,
L23419,
X07203,
X12530,
AP003127,
L23416,
M27394,
X07204,
BC002807,
L23417,
AP001034
Ensembl:
ENSG00000156738
KO:
hsa:931
|
| Nucleutide sequences |
EMBL-CDS:
AAA88911.1,
CAA30180.1,
CAA31046.1,
EAW73889.1,
BAG61836.1,
AAA35581.1,
CAA30179.1,
AAH02807.1,
EAW73892.1,
EAW73891.1
Gene_ORFName:
hCG_40403
Ensembl_TRS:
ENST00000534668,
ENST00000389939,
ENST00000345732,
ENST00000528313,
ENST00000674194
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000314620,
ENSP00000374589,
ENSP00000432270,
ENSP00000433277,
ENSP00000501369
RefSeq:
NP_690606.1,
NP_690605.1,
NP_068769.2
|
| Others |
UniRef100:
UniRef100_P11836
UniRef90:
UniRef90_P11836
UniRef50:
UniRef50_P11836
UniGene:
Hs.712553
CCDS:
CCDS31570.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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